Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 929033..929603 Replicon chromosome
Accession NZ_CP032910
Organism Helicobacter pylori strain 20-A-EK1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D4H71_RS04585 Protein ID WP_139548257.1
Coordinates 929033..929305 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D4H71_RS04590 Protein ID WP_139548258.1
Coordinates 929292..929603 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4H71_RS04565 925669..926436 - 768 WP_042630550.1 ABC transporter ATP-binding protein -
D4H71_RS04570 926436..927416 - 981 WP_139548255.1 iron ABC transporter permease -
D4H71_RS04575 927409..928263 - 855 WP_139548256.1 SDR family oxidoreductase -
D4H71_RS04580 928403..928927 + 525 WP_001135603.1 acyl-CoA thioesterase -
D4H71_RS04585 929033..929305 - 273 WP_139548257.1 type II toxin-antitoxin system YafQ family toxin Toxin
D4H71_RS04590 929292..929603 - 312 WP_139548258.1 hypothetical protein Antitoxin
D4H71_RS04595 929682..929884 - 203 Protein_865 type II toxin-antitoxin system YafQ family toxin -
D4H71_RS04600 929919..930296 - 378 WP_139548259.1 hypothetical protein -
D4H71_RS04605 930622..932805 - 2184 WP_139548260.1 outer membrane beta-barrel protein -
D4H71_RS04625 933356..933999 + 644 Protein_868 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10498.55 Da        Isoelectric Point: 10.1037

>T112832 WP_139548257.1 NZ_CP032910:c929305-929033 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYKVVENLATEQPLAPKYKDHPLKGTLKDFRECHLKPDLLLVYQIKKPKNTLFL
ARLGSHSELF

Download         Length: 273 bp

>T112832 NZ_CP032910:c929305-929033 [Helicobacter pylori]
ATGCTGATGATTGAAACCAGTAAAAAATTTGATAAGGATCTTAAAATTCTTGTTAAAAACGGATTTGATTTAAAGCTTTT
ATATAAAGTGGTTGAAAATTTAGCCACAGAGCAACCCCTAGCTCCCAAATACAAAGACCACCCACTCAAAGGCACTTTAA
AAGATTTTAGGGAATGCCACCTAAAACCGGATTTATTGCTTGTCTATCAAATTAAAAAACCAAAAAACACTCTCTTTTTA
GCAAGGTTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12322.15 Da        Isoelectric Point: 9.8823

>AT112832 WP_139548258.1 NZ_CP032910:c929603-929292 [Helicobacter pylori]
MPNTTAEKDYTKYSEKQLFNFLNSIKTKQKRALEKLKEIQIQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKDH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT112832 NZ_CP032910:c929603-929292 [Helicobacter pylori]
ATGCCTAACACCACCGCAGAAAAAGACTACACAAAATACAGCGAAAAACAGCTTTTTAATTTTTTAAATTCTATCAAGAC
CAAGCAAAAAAGAGCGTTAGAAAAATTGAAAGAAATCCAAATTCAAAAACAAAGGATTAAAAAAGCGCTCCAATTTAAAG
CGCTCCATTTAACCGAAAACGGATACACCATAGAAGAAGAGCGAGAAATCTTAGCAAGGGCTAAAGATACTAAGGACCAC
CTTTGTTTTAAAAGCGTAGAGGATTTTAAAAAACATTGTGAAAACTTAAGATTTAAAAATGCTGATGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References