Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1942689..1942834 Replicon chromosome
Accession NZ_CP032831
Organism Klebsiella pneumoniae strain INF078

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1942725..1942827 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1942689..1942834 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D9K63_RS09585 1937819..1939879 + 2061 WP_004151449.1 oligopeptidase B -
D9K63_RS09590 1939883..1940542 - 660 WP_002911407.1 exodeoxyribonuclease X -
D9K63_RS09595 1940621..1940851 - 231 WP_002911406.1 DNA polymerase III subunit theta -
D9K63_RS09600 1940964..1941338 + 375 WP_004151448.1 CopC domain-containing protein YobA -
D9K63_RS09605 1941342..1942211 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
D9K63_RS09610 1942228..1942566 + 339 WP_002911404.1 YebY family protein -
- 1942689..1942834 - 146 - - Antitoxin
- 1942725..1942827 + 103 - - Toxin
D9K63_RS28815 1943202..1943345 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
D9K63_RS09620 1943450..1944418 - 969 WP_004151446.1 VirK/YbjX family protein -
D9K63_RS09625 1944575..1945228 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
D9K63_RS09630 1945225..1945416 - 192 WP_002911395.1 YebW family protein -
D9K63_RS09635 1945514..1945753 - 240 WP_002911393.1 YebV family protein -
D9K63_RS09640 1945869..1947302 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1870023..1960230 90207


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T112603 NZ_CP032831:1942725-1942827 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT112603 NZ_CP032831:c1942834-1942689 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References