Detailed information of TA system TA112596

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 776096..776672
• Replicon: chromosome
• Accession: NZ_CP032823
• Organism: Arcobacter cryaerophilus ATCC 43158

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ACRYA_RS03895
• Protein ID: WP_105917681.1
• Coordinates: 776340..776672 (+)
• Length: 111 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ACRYA_RS03890
• Protein ID: WP_105917682.1
• Coordinates: 776096..776350 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACRYA_RS03875	773144..773878	+	735	WP_165786096.1	glycosyltransferase	-
ACRYA_RS03880	773890..775002	+	1113	WP_105917684.1	glycosyltransferase family 4 protein	-
ACRYA_RS03885	775101..776027	+	927	WP_105917683.1	sugar transferase	-
ACRYA_RS03890	776096..776350	+	255	WP_105917682.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ACRYA_RS03895	776340..776672	+	333	WP_105917681.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ACRYA_RS03900	776685..777743	+	1059	WP_105917680.1	UDP-glucose 4-epimerase GalE	-
ACRYA_RS03905	777897..778472	+	576	WP_165786095.1	hypothetical protein	-
ACRYA_RS03910	778506..779483	-	978	WP_105917678.1	catalase	-
ACRYA_RS03915	779583..780494	-	912	WP_105917677.1	AEC family transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	rfbD / wbtL	745295..777743	32448

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-69)

Sequences

Toxin

Protein

• Length: 111 a.a.
• Molecular weight: 13100.54 Da
• Isoelectric Point: 10.5036

>T112596 WP_105917681.1 NZ_CP032823:776340-776672 [Arcobacter cryaerophilus ATCC 43158]
MIYKIKFTPISYKEWNSLDSAIKLQFKKKLEKIVHNPRIVKNKLSGYKNIYKIKLRSSGFRLACEVKEEQIVILVLSVGK
RENNKVYEKLKESMTKETDKEEFKNFNKII

Nucleotide

• Length: 333 bp

>T112596 NZ_CP032823:776340-776672 [Arcobacter cryaerophilus ATCC 43158]
ATGATTTATAAAATAAAATTTACTCCAATTTCATATAAAGAGTGGAATAGTCTTGATTCAGCTATTAAACTACAATTTAA
AAAAAAATTAGAAAAAATTGTACATAATCCAAGAATAGTAAAAAATAAATTAAGTGGATATAAAAATATATATAAAATAA
AGCTAAGAAGCTCTGGTTTTAGGCTAGCATGTGAAGTAAAAGAAGAACAAATAGTTATATTAGTTTTAAGTGTAGGAAAA
AGAGAAAATAATAAAGTATATGAAAAACTGAAAGAAAGTATGACAAAAGAGACAGATAAAGAAGAGTTTAAAAATTTTAA
CAAAATAATATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9642.02 Da
• Isoelectric Point: 4.1473

>AT112596 WP_105917682.1 NZ_CP032823:776096-776350 [Arcobacter cryaerophilus ATCC 43158]
MQPILSKYTASITELKKSPSQLLKDTGDEAVAILNHNITSAYLVPSSLYEKMMDIIDDYYLIKELEERLSYKEDELIEVS
LNDL

Nucleotide

• Length: 255 bp

>AT112596 NZ_CP032823:776096-776350 [Arcobacter cryaerophilus ATCC 43158]
ATGCAACCAATCTTGTCAAAATATACAGCAAGTATAACAGAACTTAAAAAATCACCTTCACAACTACTAAAAGATACAGG
AGATGAAGCAGTAGCAATTTTAAATCACAATATAACTAGTGCATATCTAGTACCAAGTTCTTTATATGAAAAGATGATGG
ATATTATAGATGATTATTATTTAATAAAAGAGCTAGAAGAGAGATTAAGCTATAAAGAAGATGAGCTAATAGAGGTCTCT
TTAAATGATTTATAA