Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2295539..2295773 Replicon chromosome
Accession NZ_CP032811
Organism Escherichia coli strain ERL03-1416

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2295669..2295772 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2295539..2295773 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z67_RS11720 2292094..2292756 - 663 WP_000944244.1 exodeoxyribonuclease X -
D8Z67_RS11725 2292780..2293436 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z67_RS11730 2293538..2293768 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z67_RS11735 2293907..2294281 + 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z67_RS11740 2294285..2295157 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z67_RS11745 2295170..2295511 + 342 WP_000976483.1 YebY family protein -
- 2295539..2295773 - 235 - - Antitoxin
- 2295669..2295772 + 104 - - Toxin
D8Z67_RS11750 2295904..2296980 - 1077 WP_045893699.1 phage integrase Arm DNA-binding domain-containing protein -
D8Z67_RS11755 2296946..2297227 - 282 WP_001311878.1 excisionase -
D8Z67_RS11760 2297334..2297522 - 189 WP_001356607.1 DUF1187 family protein -
- 2297338..2297516 + 179 NuclAT_0 - -
- 2297338..2297516 + 179 NuclAT_0 - -
- 2297338..2297516 + 179 NuclAT_0 - -
- 2297338..2297516 + 179 NuclAT_0 - -
D8Z67_RS11765 2297515..2297709 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
D8Z67_RS11770 2297766..2298575 - 810 WP_000166313.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2275459..2357017 81558


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112553 NZ_CP032811:2295669-2295772 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT112553 NZ_CP032811:c2295773-2295539 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References