Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2171717..2171988 Replicon chromosome
Accession NZ_CP032805
Organism Escherichia coli strain ERL05-0623

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2171847..2171950 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2171717..2171988 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z69_RS10920 2168272..2168934 - 663 WP_000944243.1 exodeoxyribonuclease X -
D8Z69_RS10925 2168958..2169614 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z69_RS10930 2169716..2169946 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z69_RS10935 2170085..2170459 + 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z69_RS10940 2170463..2171335 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z69_RS10945 2171348..2171689 + 342 WP_000976483.1 YebY family protein -
- 2171717..2171988 - 272 - - Antitoxin
- 2171847..2171950 + 104 - - Toxin
D8Z69_RS10950 2172085..2172741 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
D8Z69_RS10955 2172742..2172933 - 192 WP_001296140.1 YebW family protein -
D8Z69_RS10960 2173038..2173274 - 237 WP_001295499.1 DUF1480 family protein -
D8Z69_RS10965 2173392..2174831 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112479 NZ_CP032805:2171847-2171950 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT112479 NZ_CP032805:c2171988-2171717 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References