Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2338962..2339233 Replicon chromosome
Accession NZ_CP032803
Organism Escherichia coli strain ERL05-1306

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2339092..2339195 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2338962..2339233 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z70_RS12100 2335517..2336179 - 663 WP_000944243.1 exodeoxyribonuclease X -
D8Z70_RS12105 2336203..2336859 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z70_RS12110 2336961..2337191 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z70_RS12115 2337330..2337704 + 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z70_RS12120 2337708..2338580 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z70_RS12125 2338593..2338934 + 342 WP_000976483.1 YebY family protein -
- 2338962..2339233 - 272 - - Antitoxin
- 2339092..2339195 + 104 - - Toxin
D8Z70_RS12130 2339330..2339986 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
D8Z70_RS12135 2339987..2340178 - 192 WP_001296140.1 YebW family protein -
D8Z70_RS12140 2340283..2340519 - 237 WP_001295499.1 DUF1480 family protein -
D8Z70_RS12145 2340637..2342076 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112442 NZ_CP032803:2339092-2339195 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT112442 NZ_CP032803:c2339233-2338962 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References