Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2285983..2286217 Replicon chromosome
Accession NZ_CP032801
Organism Escherichia coli strain ERL06-2442

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2286113..2286216 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2285983..2286217 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z71_RS11685 2282538..2283200 - 663 WP_000944244.1 exodeoxyribonuclease X -
D8Z71_RS11690 2283224..2283880 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z71_RS11695 2283982..2284212 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z71_RS11700 2284351..2284725 + 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z71_RS11705 2284729..2285601 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z71_RS11710 2285614..2285955 + 342 WP_000976483.1 YebY family protein -
- 2285983..2286217 - 235 - - Antitoxin
- 2286113..2286216 + 104 - - Toxin
D8Z71_RS11715 2286348..2287424 - 1077 WP_045893699.1 phage integrase Arm DNA-binding domain-containing protein -
D8Z71_RS11720 2287390..2287671 - 282 WP_001311878.1 excisionase -
D8Z71_RS11725 2287778..2287966 - 189 WP_001356607.1 DUF1187 family protein -
- 2287782..2287960 + 179 NuclAT_0 - -
- 2287782..2287960 + 179 NuclAT_0 - -
- 2287782..2287960 + 179 NuclAT_0 - -
- 2287782..2287960 + 179 NuclAT_0 - -
D8Z71_RS11730 2287959..2288153 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
D8Z71_RS11735 2288210..2289019 - 810 WP_000166313.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2265903..2347464 81561


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112406 NZ_CP032801:2286113-2286216 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT112406 NZ_CP032801:c2286217-2285983 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References