Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2196456..2196727 Replicon chromosome
Accession NZ_CP032793
Organism Escherichia coli strain NZRM3614

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2196586..2196689 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2196456..2196727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z74_RS11100 2193011..2193673 - 663 WP_000944243.1 exodeoxyribonuclease X -
D8Z74_RS11105 2193697..2194353 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z74_RS11110 2194455..2194685 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z74_RS11115 2194824..2195198 + 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z74_RS11120 2195202..2196074 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z74_RS11125 2196087..2196428 + 342 WP_000976483.1 YebY family protein -
- 2196456..2196727 - 272 - - Antitoxin
- 2196586..2196689 + 104 - - Toxin
D8Z74_RS11130 2196824..2197480 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
D8Z74_RS11135 2197481..2197672 - 192 WP_001296140.1 YebW family protein -
D8Z74_RS11140 2197777..2198013 - 237 WP_001295499.1 DUF1480 family protein -
D8Z74_RS11145 2198131..2199570 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112297 NZ_CP032793:2196586-2196689 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT112297 NZ_CP032793:c2196727-2196456 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References