Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2242799..2243033 Replicon chromosome
Accession NZ_CP032789
Organism Escherichia coli strain NZRM4169

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2242929..2243032 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2242799..2243033 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z76_RS11470 2239354..2240016 - 663 WP_000944243.1 exodeoxyribonuclease X -
D8Z76_RS11475 2240040..2240696 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z76_RS11480 2240798..2241028 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z76_RS11485 2241167..2241541 + 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z76_RS11490 2241545..2242417 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z76_RS11495 2242430..2242771 + 342 WP_000976483.1 YebY family protein -
- 2242799..2243033 - 235 - - Antitoxin
- 2242929..2243032 + 104 - - Toxin
D8Z76_RS11500 2243164..2244240 - 1077 WP_001189085.1 phage integrase Arm DNA-binding domain-containing protein -
D8Z76_RS11505 2244206..2244487 - 282 WP_005127484.1 excisionase -
D8Z76_RS11510 2244594..2244782 - 189 WP_151538908.1 DUF1187 family protein -
- 2244598..2244776 + 179 NuclAT_0 - -
- 2244598..2244776 + 179 NuclAT_0 - -
- 2244598..2244776 + 179 NuclAT_0 - -
- 2244598..2244776 + 179 NuclAT_0 - -
D8Z76_RS11515 2244775..2244969 - 195 WP_010989194.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
D8Z76_RS11520 2245033..2246085 - 1053 WP_001004413.1 recombinase RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleC 2237297..2313049 75752


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112218 NZ_CP032789:2242929-2243032 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT112218 NZ_CP032789:c2243033-2242799 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References