Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2998781..2999422 Replicon chromosome
Accession NZ_CP032743
Organism Acinetobacter baumannii strain C25

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag D7A46_RS15245 Protein ID WP_000607077.1
Coordinates 2999033..2999422 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag D7A46_RS15240 Protein ID WP_011860336.1
Coordinates 2998781..2999026 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7A46_RS15220 2994285..2995292 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
D7A46_RS15225 2995311..2995688 + 378 WP_001216380.1 50S ribosomal protein L17 -
D7A46_RS15230 2995870..2997360 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
D7A46_RS15235 2997409..2998581 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
D7A46_RS15240 2998781..2999026 + 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
D7A46_RS15245 2999033..2999422 + 390 WP_000607077.1 membrane protein Toxin
D7A46_RS15250 3000192..3001277 + 1086 WP_000049106.1 hypothetical protein -
D7A46_RS15255 3001355..3001921 + 567 WP_000651538.1 rhombosortase -
D7A46_RS15260 3002109..3004304 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T112201 WP_000607077.1 NZ_CP032743:2999033-2999422 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T112201 NZ_CP032743:2999033-2999422 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT112201 WP_011860336.1 NZ_CP032743:2998781-2999026 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT112201 NZ_CP032743:2998781-2999026 [Acinetobacter baumannii]
ATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTTTGACCCTTATGT
GAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAGACCCTGATTTAC
TAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAACACTATGTTCAT
GGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References