Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 1413538..1414208 Replicon chromosome
Accession NZ_CP032707
Organism Brevundimonas naejangsanensis strain BRV3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D8I30_RS06625 Protein ID WP_121482039.1
Coordinates 1413538..1413957 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D8I30_RS06630 Protein ID WP_121482040.1
Coordinates 1413957..1414208 (-) Length 84 a.a.

Genomic Context

D8I30_RS06610D8I30_RS06635D8I30_RS06640D8I30_RS06645D8I30_RS06615D8I30_RS06620D8I30_RS14385D8I30_RS06625D8I30_RS06630
Location: 1408907..1409845 (939 bp)
Type: Others
Protein ID: WP_121482036.1
Location: 1414316..1417162 (2847 bp)
Type: Others
Protein ID: WP_121482041.1
Location: 1417406..1417879 (474 bp)
Type: Others
Protein ID: WP_121482042.1
Location: 1418100..1419158 (1059 bp)
Type: Others
Protein ID: WP_121482043.1
Location: 1409855..1410586 (732 bp)
Type: Others
Protein ID: WP_121482037.1
Location: 1410753..1413383 (2631 bp)
Type: Others
Protein ID: WP_121482038.1
Location: 1413380..1413517 (138 bp)
Type: Others
Protein ID: WP_162938824.1
Location: 1413538..1413957 (420 bp)
Type: Toxin
Protein ID: WP_121482039.1
Location: 1413957..1414208 (252 bp)
Type: Antitoxin
Protein ID: WP_121482040.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D8I30_RS066101408907..1409845+939WP_121482036.1pirin family protein-
D8I30_RS066151409855..1410586-732WP_121482037.1ligase-associated DNA damage response endonuclease PdeM-
D8I30_RS066201410753..1413383-2631WP_121482038.1ligase-associated DNA damage response DEXH box helicase-
D8I30_RS143851413380..1413517-138WP_162938824.1hypothetical protein-
D8I30_RS066251413538..1413957-420WP_121482039.1type II toxin-antitoxin system VapC family toxinToxin
D8I30_RS066301413957..1414208-252WP_121482040.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
D8I30_RS066351414316..1417162+2847WP_121482041.1ATP-dependent DNA helicase-
D8I30_RS066401417406..1417879+474WP_121482042.1Cys-tRNA(Pro) deacylase-
D8I30_RS066451418100..1419158+1059WP_121482043.1DUF2125 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-67)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15638.80 Da        Isoelectric Point: 4.9890

>T112182 WP_121482039.1 NZ_CP032707:c1413957-1413538 [Brevundimonas naejangsanensis]
MFLLDTNAISEPKRARPDAGLIGWLSDQLLSDLHLSVITVGELRRGIVRLEPGRRRDDLDYWLSDLVLRFDDRILPVDLD
VTERWASLAEAARTAGRASDMTDELIAATAHVHGLAVVTRNVRHFEPLGCRVLSPWSEE

Download         Length: 420 bp

>T112182 NZ_CP032707:c1413957-1413538 [Brevundimonas naejangsanensis]
ATGTTTCTGCTCGACACCAACGCCATCAGCGAGCCGAAGCGCGCGCGACCGGACGCGGGCCTGATCGGCTGGCTCAGCGA
TCAGCTGCTGTCGGACCTGCACCTCAGCGTCATCACGGTGGGGGAGCTTCGGCGCGGCATCGTCCGCCTCGAACCCGGCC
GCCGACGCGACGATCTCGACTATTGGCTTAGCGACCTGGTGCTGAGGTTCGATGACCGGATTCTGCCGGTCGATCTGGAC
GTCACCGAGCGCTGGGCCTCTCTAGCAGAGGCCGCGCGAACGGCGGGTCGAGCCTCGGACATGACGGACGAACTGATCGC
GGCGACCGCTCATGTCCATGGCCTGGCGGTGGTAACCCGCAACGTCCGGCATTTCGAGCCTCTGGGCTGCCGGGTGCTCT
CGCCATGGAGCGAAGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9394.51 Da        Isoelectric Point: 5.7235

>AT112182 WP_121482040.1 NZ_CP032707:c1414208-1413957 [Brevundimonas naejangsanensis]
MSWSVAKAKDNLSEVIRRSRSEGPQEISLHGEAAAVVLSAEDFRRLKDPRAAHDFKDWLLNGPSLEGVDLERDRRPTRDI
DPL

Download         Length: 252 bp

>AT112182 NZ_CP032707:c1414208-1413957 [Brevundimonas naejangsanensis]
ATGAGCTGGAGCGTCGCCAAGGCGAAGGACAATCTCTCGGAGGTCATCCGACGTTCGCGCAGCGAGGGGCCGCAGGAGAT
TTCCCTGCACGGAGAGGCCGCCGCCGTCGTGTTGTCGGCTGAGGACTTCCGCCGGTTGAAAGACCCTCGCGCGGCCCATG
ATTTCAAGGACTGGCTGCTGAACGGTCCGTCGCTGGAAGGCGTCGATCTGGAGCGAGATCGCCGTCCGACGCGGGACATC
GACCCGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References