112181

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 282790..284447 Replicon chromosome
Accession NZ_CP032707
Organism Brevundimonas naejangsanensis strain BRV3

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag D8I30_RS01285 Protein ID WP_121481132.1
Coordinates 283845..284447 (-) Length 201 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag D8I30_RS01280 Protein ID WP_121481131.1
Coordinates 282790..283836 (-) Length 349 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8I30_RS01260 278929..279106 - 178 Protein_254 IS5/IS1182 family transposase -
D8I30_RS01265 279288..280577 - 1290 WP_121481128.1 three-Cys-motif partner protein TcmP -
D8I30_RS01270 280605..281378 - 774 WP_121481129.1 DUF5131 family protein -
D8I30_RS01275 281611..282777 + 1167 WP_121481130.1 three-Cys-motif partner protein TcmP -
D8I30_RS01280 282790..283836 - 1047 WP_121481131.1 macro domain-containing protein Antitoxin
D8I30_RS01285 283845..284447 - 603 WP_121481132.1 DUF4433 domain-containing protein Toxin
D8I30_RS14535 284631..285044 - 414 WP_205570759.1 IS5 family transposase -
D8I30_RS14540 285041..285259 - 219 WP_205570735.1 transposase -
D8I30_RS01295 285442..285705 - 264 WP_121481133.1 helix-turn-helix domain-containing protein -
D8I30_RS01300 285778..286296 + 519 WP_162938771.1 hypothetical protein -
D8I30_RS01305 286327..287154 + 828 WP_162938772.1 hypothetical protein -
D8I30_RS01310 287157..289241 - 2085 WP_121481136.1 recombinase family protein -
D8I30_RS01315 289238..289444 - 207 WP_121481137.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 268206..298545 30339


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(1-200)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 201 a.a.        Molecular weight: 21655.44 Da        Isoelectric Point: 7.9127

>T112181 WP_121481132.1 NZ_CP032707:c284447-283845 [Brevundimonas naejangsanensis]
MTHVGNLQTILAAGELRATARLNAQGTAFTNIAYSSIQAQRAGKVVTCGPGGSLHDYVPFYFTRRSPMLYTINRGNVPCE
GGQGALVHLVSNAQAVAAAGLGFAFSDGHGIMAYSSFYDDLAHLGEIDWDVIAAGQWADTVEDGDRKRRKQAEFLVRDRF
PIALLQGAVVQTQARADQVNAIAASARQPLRVVVRPDWYY

Download         Length: 603 bp

>T112181 NZ_CP032707:c284447-283845 [Brevundimonas naejangsanensis]
ATGACCCATGTCGGAAATCTGCAGACGATCCTGGCTGCCGGGGAGTTGCGGGCGACGGCGAGGCTGAATGCGCAAGGTAC
CGCCTTCACCAACATCGCTTACAGTTCCATCCAGGCGCAACGCGCGGGGAAGGTTGTCACTTGCGGGCCTGGCGGGTCGC
TCCATGACTATGTGCCGTTCTATTTCACCCGGCGCAGCCCGATGCTCTACACGATCAACCGCGGCAACGTGCCGTGTGAA
GGTGGGCAGGGTGCACTCGTCCACCTAGTTTCAAACGCCCAAGCGGTCGCGGCGGCCGGTCTGGGGTTCGCCTTTAGTGA
CGGCCATGGAATCATGGCCTACTCCAGTTTCTACGATGACCTGGCGCATCTGGGTGAGATCGACTGGGATGTCATCGCGG
CCGGTCAATGGGCGGATACGGTTGAAGATGGGGATCGCAAGCGGCGCAAACAGGCCGAGTTCCTCGTGAGGGACCGGTTT
CCAATCGCCTTGCTTCAAGGGGCCGTGGTTCAGACACAGGCTCGCGCCGATCAGGTGAACGCGATCGCGGCGAGCGCCAG
GCAGCCGTTGCGGGTGGTCGTTCGCCCCGACTGGTACTATTGA

Antitoxin


Download         Length: 349 a.a.        Molecular weight: 38562.89 Da        Isoelectric Point: 6.2864

>AT112181 WP_121481131.1 NZ_CP032707:c283836-282790 [Brevundimonas naejangsanensis]
MIKLAQGDLLQSGAEAIINTVNCVGVMGKGIALQFKQEFPGNYEAYRRACDAGEVRLGEMFVFDTGSMINPRWIINFPTK
GHWKAKSRIDDIASGLKDLRRVIETLGVRSIAVPPLGCGNGGLDWADVEPMIRTALGNLEDVEVMLFPPSGAPKVDSMRV
NTARPNMSRGRALVLSLLGLYGAAGYRHSLLEIQKLTYFLQESGEDLKLGFQKHHYGPYAENLNHVLQRIEGHFIRGYGD
RSQAAEIAVLDDGRQEAEAFLDADETAQARLDRVAELIEGFETPYGLELLSTVHWIATHDAEAAREPDRVVDAVRSWNPR
KAATLREPHIRTALIHLRSHGWISEQAA

Download         Length: 1047 bp

>AT112181 NZ_CP032707:c283836-282790 [Brevundimonas naejangsanensis]
ATGATCAAACTCGCCCAGGGCGATCTCCTCCAGTCCGGTGCCGAAGCCATTATCAACACCGTCAATTGCGTCGGTGTGAT
GGGCAAGGGTATCGCTCTGCAGTTCAAGCAGGAGTTTCCGGGAAACTATGAAGCCTATCGGCGCGCCTGCGATGCGGGCG
AGGTGCGTTTGGGCGAGATGTTCGTGTTCGACACCGGCAGTATGATCAACCCGCGTTGGATCATCAACTTTCCAACCAAG
GGGCACTGGAAAGCCAAGTCCCGGATCGACGATATCGCGTCCGGTTTGAAGGATCTCAGGCGAGTGATCGAAACCCTTGG
TGTACGGTCCATCGCCGTTCCGCCGCTGGGTTGCGGCAATGGAGGTCTGGACTGGGCCGACGTCGAGCCCATGATCCGAA
CGGCCTTGGGCAATCTGGAAGATGTTGAAGTAATGCTGTTCCCGCCTTCGGGAGCGCCCAAGGTCGACAGCATGCGGGTC
AATACCGCGCGGCCCAACATGAGCCGGGGCAGGGCCCTAGTCCTGAGCCTTCTGGGGCTCTATGGCGCCGCCGGATATCG
ACACAGCCTGCTCGAGATTCAGAAGCTGACCTATTTCCTCCAGGAGTCGGGCGAGGACCTCAAGCTGGGGTTCCAGAAGC
ATCACTACGGCCCTTATGCCGAGAACCTGAACCATGTGCTGCAGCGGATCGAAGGGCATTTCATCCGCGGTTATGGCGAT
CGCAGCCAGGCGGCCGAGATCGCGGTGCTCGACGATGGACGGCAAGAGGCCGAGGCTTTTCTCGACGCCGACGAGACCGC
CCAGGCGCGGCTGGATCGGGTTGCCGAGCTGATCGAAGGGTTCGAGACTCCCTACGGTCTGGAACTGCTATCGACCGTGC
ACTGGATCGCGACCCATGACGCCGAGGCGGCTCGCGAGCCGGACCGGGTGGTAGACGCCGTTCGATCTTGGAACCCGCGC
AAGGCGGCGACCCTGCGTGAGCCCCATATCCGAACGGCGCTCATCCATCTGCGCTCGCACGGCTGGATCAGTGAACAGGC
CGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References