Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 58885..59528 Replicon plasmid unnamed2
Accession NZ_CP032704
Organism Pantoea dispersa strain DSM 32899

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag D8B20_RS20290 Protein ID WP_145891745.1
Coordinates 59112..59528 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag D8B20_RS20285 Protein ID WP_145891743.1
Coordinates 58885..59115 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8B20_RS20265 55773..56285 + 513 WP_145891736.1 hypothetical protein -
D8B20_RS20270 56499..57260 - 762 WP_145891738.1 site-specific integrase -
D8B20_RS20275 57287..57919 - 633 WP_145891739.1 hypothetical protein -
D8B20_RS20280 58011..58313 - 303 WP_145891741.1 hypothetical protein -
D8B20_RS20285 58885..59115 + 231 WP_145891743.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
D8B20_RS20290 59112..59528 + 417 WP_145891745.1 type II toxin-antitoxin system VapC family toxin Toxin
D8B20_RS20295 59569..60447 - 879 WP_145891747.1 restriction endonuclease -
D8B20_RS20300 60686..61639 + 954 WP_145891749.1 hypothetical protein -
D8B20_RS20305 61738..62721 + 984 WP_145891751.1 hypothetical protein -
D8B20_RS20310 63118..64122 + 1005 WP_145891753.1 Abi family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..275665 275665


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-49)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15157.64 Da        Isoelectric Point: 9.1725

>T112178 WP_145891745.1 NZ_CP032704:59112-59528 [Pantoea dispersa]
VKKTYMLDTNICSFIMREKPETVIKRLEQVVLRGHRIVVSAVTYAEMRFGATGPKASPRHMQLVDAFCARLDAVLPWDRA
AVDATTEIKVSLRLAGTPIGPNDTAIAGHAIAAGAVLVTNNTREFERVPGLTLEDWVK

Download         Length: 417 bp

>T112178 NZ_CP032704:59112-59528 [Pantoea dispersa]
GTGAAAAAAACGTATATGCTGGACACTAATATCTGCTCATTCATCATGCGCGAGAAGCCGGAGACCGTGATAAAACGCCT
GGAGCAGGTGGTGCTGCGCGGTCATCGTATTGTGGTCTCGGCCGTGACCTACGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCTCGCCACATGCAGCTGGTTGACGCGTTCTGCGCCCGCCTTGATGCCGTCCTGCCCTGGGACCGTGCC
GCGGTGGATGCGACCACGGAGATTAAAGTTTCGCTGCGGCTGGCCGGGACACCGATCGGTCCGAACGACACTGCGATCGC
CGGGCACGCCATTGCCGCCGGCGCCGTGCTGGTGACGAATAATACGCGGGAGTTTGAGCGGGTACCGGGTCTGACGCTGG
AAGACTGGGTGAAGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8714.79 Da        Isoelectric Point: 4.3654

>AT112178 WP_145891743.1 NZ_CP032704:58885-59115 [Pantoea dispersa]
MRTVSVFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRPTWGSFLGFEKADPDFMAEREDVVSDEGRFDL

Download         Length: 231 bp

>AT112178 NZ_CP032704:58885-59115 [Pantoea dispersa]
ATGCGAACTGTATCTGTGTTTAAAAATGGCAATAACCGCGCCATCCGCCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAAATCGTCCGGGAAGGGGACAGCATCATCCTGCGTCCCGTCCGGCCGACCTGGGGCTCATTCCTGGGGTTCG
AAAAAGCCGATCCGGATTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References