Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1077634..1079113 Replicon plasmid pRCCGE525c
Accession NZ_CP032695
Organism Rhizobium jaguaris strain CCGE525

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag CCGE525_RS27295 Protein ID WP_120707397.1
Coordinates 1078244..1079113 (+) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag CCGE525_RS27290 Protein ID WP_120707396.1
Coordinates 1077634..1078251 (+) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE525_RS27270 1073410..1074960 - 1551 WP_120707394.1 ABC transporter substrate-binding protein -
CCGE525_RS27275 1074973..1076196 - 1224 WP_120708650.1 M20/M25/M40 family metallo-hydrolase -
CCGE525_RS27280 1076425..1077180 + 756 WP_120707395.1 GntR family transcriptional regulator -
CCGE525_RS27285 1077251..1077485 + 235 Protein_1001 DNA polymerase -
CCGE525_RS27290 1077634..1078251 + 618 WP_120707396.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
CCGE525_RS27295 1078244..1079113 + 870 WP_120707397.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CCGE525_RS27300 1079745..1081190 - 1446 WP_120707398.1 aldehyde dehydrogenase -
CCGE525_RS27305 1081217..1082002 - 786 WP_120707399.1 coniferyl-alcohol dehydrogenase -
CCGE525_RS27310 1082044..1083064 - 1021 Protein_1006 branched-chain amino acid ABC transporter permease -
CCGE525_RS27315 1083061..1083957 - 897 WP_120707400.1 branched-chain amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - tssC-5 / katA 1..2584926 2584926


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-265)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(14-56)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32305.07 Da        Isoelectric Point: 5.7408

>T112169 WP_120707397.1 NZ_CP032695:1078244-1079113 [Rhizobium jaguaris]
MAKETKNLGASVRARLLQLAKASGQSFDLVLTRFALERLLFRLSQSPHAGRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
SPEPDPMLKTFREILAQQADDGVTFDAETLRVDRIREALEYGGLRLRVVASISGARIALTIDIGFGDALEPGAEVLDYPS
MLGFPMPRLRAYARETVIAEKFQAMVMLGRANSRMKDFYDIWILSRSFDFNDDRLARAITATFERRETPIPTEAPDALTD
AFAKDEEKQRQWHAFVESVAHEPGDLTDVVAEIATFLMPHAVAAARLGK

Download         Length: 870 bp

>T112169 NZ_CP032695:1078244-1079113 [Rhizobium jaguaris]
ATGGCTAAAGAAACCAAAAATCTCGGCGCCTCGGTGCGCGCGCGCCTGTTGCAACTCGCCAAGGCAAGCGGGCAAAGCTT
CGATTTGGTTCTGACGCGTTTTGCGCTTGAGCGGTTACTATTCCGGCTCAGCCAGTCACCCCATGCGGGCCGTTTTGTGC
TGAAGGGTGCGATGCTGATGATGAGTTGGTTTGACGATCCGCACCGCGGCACGCGTGATCTCGACCTTTTGGGCTTTGGC
AGTCCAGAGCCGGACCCGATGCTGAAGACCTTTCGGGAGATTCTGGCGCAACAGGCTGATGATGGCGTCACGTTCGACGC
AGAAACTTTACGCGTGGATCGCATTCGCGAGGCACTAGAATATGGTGGGCTCAGGCTGCGGGTGGTCGCCTCGATCAGCG
GCGCCCGGATCGCCCTGACGATCGACATCGGGTTTGGCGATGCGCTCGAGCCTGGGGCGGAGGTGCTAGATTATCCTTCT
ATGCTCGGTTTTCCGATGCCCCGGCTCCGAGCCTATGCGCGGGAGACGGTCATTGCCGAGAAGTTCCAGGCGATGGTCAT
GCTGGGGCGTGCAAACAGCCGGATGAAGGACTTCTACGATATCTGGATTCTCAGCAGGTCATTCGATTTCAATGATGACA
GATTGGCACGTGCAATCACAGCGACTTTCGAGCGGCGCGAAACTCCGATCCCCACTGAGGCACCAGACGCCCTAACGGAC
GCCTTTGCCAAGGACGAGGAAAAGCAACGGCAATGGCACGCATTCGTTGAAAGCGTTGCACACGAACCCGGCGATCTGAC
GGACGTTGTCGCGGAGATTGCAACGTTCCTGATGCCGCACGCTGTTGCGGCTGCGAGGCTGGGCAAATGA

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22410.90 Da        Isoelectric Point: 9.6481

>AT112169 WP_120707396.1 NZ_CP032695:1077634-1078251 [Rhizobium jaguaris]
MPASITQRQIARTVLAERGIARLAELRNAGVTAATMSRMERDGEVVRLARGLYQLPDAELDANHSLAEIAKRVPKAVVCL
VSALAFHGLTDQLPRQIWLAIGRNDWAPQPNGPAMRIVRFTESLLNESVEIHVVEGVPVKIFGIAKTIADCFRYRNKIGL
SIAIEGLQETLRQRRATPGEIADQAERGGVGTVIRPYLEALTANG

Download         Length: 618 bp

>AT112169 NZ_CP032695:1077634-1078251 [Rhizobium jaguaris]
ATGCCGGCTTCCATCACTCAACGCCAAATCGCCCGAACTGTGCTCGCTGAACGCGGGATAGCACGTCTGGCGGAACTGCG
GAATGCAGGCGTGACGGCGGCCACCATGAGCCGAATGGAACGGGATGGCGAGGTCGTGCGGCTTGCCCGCGGTCTTTATC
AACTCCCCGATGCGGAGCTCGACGCCAACCACAGTCTGGCAGAGATCGCCAAACGCGTCCCGAAAGCCGTTGTCTGTCTT
GTTTCGGCCCTCGCTTTCCACGGCTTGACGGATCAACTCCCGAGGCAAATCTGGCTTGCCATAGGCCGCAACGACTGGGC
CCCACAACCGAACGGCCCTGCTATGCGCATCGTACGTTTCACAGAAAGCCTTCTCAACGAAAGCGTCGAGATCCATGTCG
TTGAAGGCGTTCCGGTGAAGATTTTTGGAATCGCCAAGACGATTGCCGATTGCTTTCGTTATCGCAACAAGATTGGCCTA
TCCATAGCGATTGAGGGGCTGCAGGAGACGCTGCGGCAACGAAGGGCTACTCCTGGCGAAATCGCTGATCAGGCCGAGCG
CGGTGGTGTTGGCACGGTGATCCGGCCGTATCTCGAGGCACTGACCGCCAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References