Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 909703..910376 Replicon plasmid pRCCGE525c
Accession NZ_CP032695
Organism Rhizobium jaguaris strain CCGE525

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CCGE525_RS26490 Protein ID WP_120707272.1
Coordinates 909703..910107 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CCGE525_RS26495 Protein ID WP_120707273.1
Coordinates 910104..910376 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE525_RS26450 905294..905680 + 387 WP_120708640.1 DUF302 domain-containing protein -
CCGE525_RS26455 905834..907381 - 1548 WP_120707267.1 Fic family protein -
CCGE525_RS26460 907579..907839 - 261 Protein_842 hypothetical protein -
CCGE525_RS26465 907862..908065 - 204 WP_120707268.1 hypothetical protein -
CCGE525_RS26470 908105..908347 - 243 WP_120707269.1 30S ribosomal protein S21 -
CCGE525_RS26475 908376..908657 - 282 WP_120707270.1 cold-shock protein -
CCGE525_RS26480 908772..908981 - 210 WP_075852595.1 cold-shock protein -
CCGE525_RS26485 909415..909630 + 216 WP_120707271.1 type II toxin-antitoxin system ParD family antitoxin -
CCGE525_RS26490 909703..910107 - 405 WP_120707272.1 type II toxin-antitoxin system VapC family toxin Toxin
CCGE525_RS26495 910104..910376 - 273 WP_120707273.1 antitoxin Antitoxin
CCGE525_RS26500 910520..911452 - 933 WP_120707274.1 LysR family transcriptional regulator -
CCGE525_RS26505 911565..912311 + 747 WP_120707275.1 SDR family oxidoreductase -
CCGE525_RS26510 912760..913833 - 1074 WP_120707276.1 extracellular solute-binding protein -
CCGE525_RS26515 913884..914660 - 777 WP_120708641.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - tssC-5 / katA 1..2584926 2584926


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(16-54)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14735.13 Da        Isoelectric Point: 4.5865

>T112167 WP_120707272.1 NZ_CP032695:c910107-909703 [Rhizobium jaguaris]
MNGYLLDTNIISDIIRNPFGPVARRIEDIDPKEICTSIIVASELRYGCAKKGSAKLLAKVESILGTLPILPLDIPSDIKY
GDICAELEAAGQTIGLNDLLIAAHACALDLTLVTDNMREFQRIRGLNLENWLER

Download         Length: 405 bp

>T112167 NZ_CP032695:c910107-909703 [Rhizobium jaguaris]
TTGAACGGGTACTTGCTTGATACGAACATCATCAGTGACATCATACGCAATCCCTTCGGACCGGTGGCACGCCGCATCGA
AGATATAGATCCCAAAGAGATTTGCACCAGCATCATTGTCGCATCGGAGTTGCGATACGGCTGCGCAAAAAAAGGATCAG
CCAAGCTACTGGCCAAGGTCGAAAGCATACTCGGAACGCTTCCGATACTGCCGCTGGATATCCCCTCCGATATCAAGTAC
GGCGACATTTGTGCGGAGTTGGAAGCTGCAGGGCAGACCATCGGCCTCAACGATCTGCTGATCGCCGCGCATGCCTGTGC
GCTAGACCTAACCCTTGTGACGGACAATATGCGCGAGTTTCAACGCATTCGCGGCCTCAATCTCGAAAACTGGCTTGAGA
GATAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10267.78 Da        Isoelectric Point: 4.8952

>AT112167 WP_120707273.1 NZ_CP032695:c910376-910104 [Rhizobium jaguaris]
MPVSLPSSRPKEVKLFRNNRSQAVRIPAEFELPGDRVLIHREGDKLIIEPVTRPSNIVELIAAWKKEAPLEPEDQFPDIE
DTPAKPENIF

Download         Length: 273 bp

>AT112167 NZ_CP032695:c910376-910104 [Rhizobium jaguaris]
ATGCCTGTTTCATTACCCTCATCAAGACCGAAAGAAGTGAAGCTGTTCCGCAACAACCGTAGCCAGGCGGTGCGCATCCC
TGCGGAATTCGAGTTACCAGGGGATCGCGTGCTAATCCACCGCGAAGGCGATAAGCTCATCATCGAGCCTGTCACCAGGC
CGTCCAATATCGTGGAGCTCATTGCCGCGTGGAAAAAGGAAGCTCCACTCGAGCCTGAAGATCAGTTCCCGGATATTGAG
GATACGCCTGCCAAGCCGGAGAACATTTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References