Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC(toxin) |
Location | 253926..254566 | Replicon | plasmid pRCCGE525c |
Accession | NZ_CP032695 | ||
Organism | Rhizobium jaguaris strain CCGE525 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | CCGE525_RS23245 | Protein ID | WP_120706733.1 |
Coordinates | 253926..254312 (-) | Length | 129 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | K0PZZ6 |
Locus tag | CCGE525_RS23250 | Protein ID | WP_007538500.1 |
Coordinates | 254312..254566 (-) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CCGE525_RS23225 | 249230..250465 | - | 1236 | WP_120706729.1 | ABC transporter substrate-binding protein | - |
CCGE525_RS23230 | 250525..251478 | - | 954 | WP_120706730.1 | sugar phosphate isomerase/epimerase | - |
CCGE525_RS23235 | 251699..252790 | + | 1092 | WP_120706731.1 | LacI family transcriptional regulator | - |
CCGE525_RS23240 | 252859..253929 | - | 1071 | WP_120706732.1 | site-specific integrase | - |
CCGE525_RS23245 | 253926..254312 | - | 387 | WP_120706733.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
CCGE525_RS23250 | 254312..254566 | - | 255 | WP_007538500.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
CCGE525_RS23255 | 254828..255763 | + | 936 | WP_120706734.1 | DUF1403 family protein | - |
CCGE525_RS23260 | 255765..256439 | + | 675 | WP_120706735.1 | SMC-Scp complex subunit ScpB | - |
CCGE525_RS23265 | 256519..257730 | - | 1212 | WP_120706736.1 | Na+/H+ antiporter NhaA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | tssC-5 / katA | 1..2584926 | 2584926 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 129 a.a. Molecular weight: 14005.77 Da Isoelectric Point: 4.5935
>T112164 WP_120706733.1 NZ_CP032695:c254312-253926 [Rhizobium jaguaris]
MVIDTSAIVAIFFNEPDALYYSERIADDPIRLISAATLVEAAMVIEGRFGEAGGAELDLWLHKTNLEAVAVTSEHADQAR
RAWRRYGKGRHPAGLNYGDCFSYALAALTGEPLLFKGNDFKQTDVEAA
MVIDTSAIVAIFFNEPDALYYSERIADDPIRLISAATLVEAAMVIEGRFGEAGGAELDLWLHKTNLEAVAVTSEHADQAR
RAWRRYGKGRHPAGLNYGDCFSYALAALTGEPLLFKGNDFKQTDVEAA
Download Length: 387 bp
>T112164 NZ_CP032695:c254312-253926 [Rhizobium jaguaris]
ATGGTGATCGATACGTCAGCGATCGTCGCGATCTTTTTCAATGAACCGGATGCCCTCTACTACAGCGAACGCATTGCCGA
CGATCCCATCCGGCTGATTTCGGCGGCAACGCTCGTCGAAGCCGCGATGGTCATCGAGGGGCGCTTCGGCGAGGCAGGCG
GAGCAGAACTCGATCTCTGGTTGCACAAGACCAATCTGGAGGCCGTTGCGGTGACCTCCGAGCATGCCGACCAGGCCCGC
CGGGCCTGGCGCCGCTACGGCAAGGGTCGCCATCCTGCCGGCCTGAATTACGGCGACTGCTTCTCCTATGCCCTCGCCGC
GCTGACCGGCGAGCCGCTGCTCTTCAAGGGGAACGACTTCAAACAGACAGATGTCGAGGCGGCATGA
ATGGTGATCGATACGTCAGCGATCGTCGCGATCTTTTTCAATGAACCGGATGCCCTCTACTACAGCGAACGCATTGCCGA
CGATCCCATCCGGCTGATTTCGGCGGCAACGCTCGTCGAAGCCGCGATGGTCATCGAGGGGCGCTTCGGCGAGGCAGGCG
GAGCAGAACTCGATCTCTGGTTGCACAAGACCAATCTGGAGGCCGTTGCGGTGACCTCCGAGCATGCCGACCAGGCCCGC
CGGGCCTGGCGCCGCTACGGCAAGGGTCGCCATCCTGCCGGCCTGAATTACGGCGACTGCTTCTCCTATGCCCTCGCCGC
GCTGACCGGCGAGCCGCTGCTCTTCAAGGGGAACGACTTCAAACAGACAGATGTCGAGGCGGCATGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9336.73 Da Isoelectric Point: 6.3656
>AT112164 WP_007538500.1 NZ_CP032695:c254566-254312 [Rhizobium jaguaris]
MALSIKDPETEKLARALAARTGETITIATRRALEERLKRMGSQAKKAALLDDMEAMRRRLSALPVLDDRSPDEIIGYDEN
GIPN
MALSIKDPETEKLARALAARTGETITIATRRALEERLKRMGSQAKKAALLDDMEAMRRRLSALPVLDDRSPDEIIGYDEN
GIPN
Download Length: 255 bp
>AT112164 NZ_CP032695:c254566-254312 [Rhizobium jaguaris]
ATGGCGCTGAGCATCAAAGACCCCGAGACGGAGAAGCTCGCGCGCGCACTCGCTGCGCGCACCGGCGAAACCATCACCAT
CGCGACGCGGCGCGCGCTGGAAGAGCGCCTCAAGCGTATGGGATCGCAAGCGAAGAAGGCTGCCCTCCTCGACGACATGG
AGGCGATGCGGCGACGCTTGAGCGCTCTGCCGGTTCTCGATGATCGCAGTCCGGATGAAATCATCGGTTACGACGAAAAC
GGTATTCCGAACTGA
ATGGCGCTGAGCATCAAAGACCCCGAGACGGAGAAGCTCGCGCGCGCACTCGCTGCGCGCACCGGCGAAACCATCACCAT
CGCGACGCGGCGCGCGCTGGAAGAGCGCCTCAAGCGTATGGGATCGCAAGCGAAGAAGGCTGCCCTCCTCGACGACATGG
AGGCGATGCGGCGACGCTTGAGCGCTCTGCCGGTTCTCGATGATCGCAGTCCGGATGAAATCATCGGTTACGACGAAAAC
GGTATTCCGAACTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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