Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/Phd-LOTUS_5_Limkain_b1
Location 3325428..3326092 Replicon chromosome
Accession NZ_CP032694
Organism Rhizobium jaguaris strain CCGE525

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CCGE525_RS16225 Protein ID WP_120705180.1
Coordinates 3325428..3325682 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CCGE525_RS16230 Protein ID WP_120705181.1
Coordinates 3325682..3326092 (+) Length 137 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE525_RS16195 3320907..3321488 + 582 WP_120705176.1 NAD(P)H-dependent oxidoreductase -
CCGE525_RS16200 3321533..3321922 - 390 WP_120706439.1 RidA family protein -
CCGE525_RS16205 3321984..3322880 - 897 WP_120705177.1 DMT family transporter -
CCGE525_RS16210 3323164..3323589 + 426 WP_120705178.1 hypothetical protein -
CCGE525_RS16215 3323640..3324251 - 612 WP_120706440.1 alpha/beta hydrolase -
CCGE525_RS16220 3324265..3325197 - 933 WP_120705179.1 VOC family protein -
CCGE525_RS16225 3325428..3325682 + 255 WP_120705180.1 type II toxin-antitoxin system Phd/YefM family antitoxin Toxin
CCGE525_RS16230 3325682..3326092 + 411 WP_120705181.1 type II toxin-antitoxin system VapC family toxin Antitoxin
CCGE525_RS16235 3326086..3326787 - 702 WP_120705182.1 uracil-DNA glycosylase -
CCGE525_RS16240 3327011..3327598 - 588 WP_120705183.1 hypothetical protein -
CCGE525_RS16245 3327746..3330193 - 2448 WP_120705184.1 FAD-dependent oxidoreductase -
CCGE525_RS16250 3330190..3331083 - 894 WP_120705185.1 phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-61)

Antitoxin

PIN domain

(2-116)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9295.28 Da        Isoelectric Point: 4.4165

>T112162 WP_120705180.1 NZ_CP032694:3325428-3325682 [Rhizobium jaguaris]
MDWPLQDAKNQFSKVVQKARSEGPQTVTLRGERAVVVLSAEDYDALRANRPSLVDDLLSGSAWDDEFADAVTTRDKAPSR
DVAF

Download         Length: 255 bp

>T112162 NZ_CP032694:3325428-3325682 [Rhizobium jaguaris]
ATGGATTGGCCGTTACAGGATGCCAAAAATCAATTCTCGAAAGTCGTGCAGAAGGCACGCAGCGAAGGTCCGCAAACGGT
GACGTTGCGCGGCGAGCGCGCGGTCGTTGTTCTCTCCGCTGAGGACTACGACGCCCTGCGGGCCAACAGGCCCAGCCTGG
TCGATGATCTGCTATCAGGATCTGCCTGGGACGATGAATTCGCCGACGCGGTGACAACGCGAGACAAGGCGCCAAGCCGG
GATGTCGCCTTCTGA

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 15129.17 Da        Isoelectric Point: 5.6094

>AT112162 WP_120705181.1 NZ_CP032694:3325682-3326092 [Rhizobium jaguaris]
MYLIDTNIISEARRGSAEATAWLRTADPSTVYLSVITLGEVMRGIALKRKSDPRTAGHLEEWLRKLRHDHSGRILPITDQ
IAVEWGRIAALRPRGDADGLIAATAIVHDLIVVTRNVSDFDDTGVPVIDPWDQESY

Download         Length: 411 bp

>AT112162 NZ_CP032694:3325682-3326092 [Rhizobium jaguaris]
ATGTATCTGATCGATACCAACATCATTTCCGAAGCGCGTCGCGGCAGCGCGGAAGCAACAGCCTGGTTACGCACGGCCGA
TCCGTCGACCGTTTATCTCAGCGTCATCACGCTCGGCGAAGTCATGCGCGGGATCGCCCTGAAGCGAAAGTCCGATCCGC
GAACCGCAGGACATCTGGAGGAATGGCTGCGTAAGCTTCGCCATGATCATAGCGGCCGTATCCTGCCCATCACAGACCAA
ATCGCCGTCGAATGGGGACGTATCGCGGCGCTGCGTCCACGCGGCGATGCCGACGGGCTGATCGCAGCCACTGCAATCGT
CCATGACCTGATTGTCGTTACACGCAATGTCAGCGATTTTGATGATACCGGCGTACCGGTGATCGATCCTTGGGATCAAG
AATCTTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References