Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 560198..560841 Replicon chromosome
Accession NZ_CP032694
Organism Rhizobium jaguaris strain CCGE525

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CCGE525_RS02775 Protein ID WP_120702948.1
Coordinates 560198..560602 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CCGE525_RS02780 Protein ID WP_120702949.1
Coordinates 560599..560841 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE525_RS02745 556199..557074 - 876 WP_120702942.1 LysR family transcriptional regulator -
CCGE525_RS02750 557172..558455 + 1284 WP_120702943.1 MFS transporter -
CCGE525_RS02755 558478..558864 + 387 WP_120702944.1 VOC family protein -
CCGE525_RS02760 558987..559328 + 342 WP_120702945.1 metalloregulator ArsR/SmtB family transcription factor -
CCGE525_RS02765 559312..559794 + 483 WP_120702946.1 SRPBCC domain-containing protein -
CCGE525_RS02770 559800..560201 + 402 WP_120702947.1 GFA family protein -
CCGE525_RS02775 560198..560602 - 405 WP_120702948.1 type II toxin-antitoxin system VapC family toxin Toxin
CCGE525_RS02780 560599..560841 - 243 WP_120702949.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CCGE525_RS02785 560908..561582 - 675 WP_120702950.1 hypothetical protein -
CCGE525_RS02790 561708..563369 - 1662 WP_120702951.1 urocanate hydratase -
CCGE525_RS02795 563410..563739 - 330 WP_120702952.1 TfoX/Sxy family protein -
CCGE525_RS02800 563758..564858 - 1101 WP_120702953.1 DUF917 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-113)

Antitoxin

SpoVT-AbrB domain

(7-42)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15045.33 Da        Isoelectric Point: 6.6459

>T112160 WP_120702948.1 NZ_CP032694:c560602-560198 [Rhizobium jaguaris]
VKYLLDSNAVIALMKGHPGFVAEIRKHKPQDFAIPAVVAHELFYRVYKGQRVAENLARVEALQFETLDFDKADARMAGEI
RANLASLGTPIGAYDVLIAGQAVARDLMLITHNVREFQLIHQLRFEDWESLPSS

Download         Length: 405 bp

>T112160 NZ_CP032694:c560602-560198 [Rhizobium jaguaris]
GTGAAATACCTGCTGGATAGTAATGCCGTCATCGCCCTGATGAAAGGTCATCCCGGTTTTGTGGCCGAGATCCGTAAACA
CAAGCCGCAGGATTTCGCTATTCCAGCCGTTGTCGCGCACGAATTGTTTTACCGCGTCTATAAAGGCCAGCGTGTTGCCG
AGAACCTTGCACGTGTTGAGGCATTGCAATTCGAGACGCTGGATTTCGACAAGGCGGATGCCCGTATGGCTGGCGAAATT
CGCGCCAACCTCGCTTCACTCGGCACACCGATCGGTGCCTATGACGTTTTGATCGCGGGTCAGGCCGTTGCCCGCGATCT
GATGCTCATTACGCACAACGTTAGGGAATTTCAGCTTATTCACCAGTTGCGTTTCGAGGACTGGGAGTCCTTGCCGAGCA
GTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9229.35 Da        Isoelectric Point: 4.1962

>AT112160 WP_120702949.1 NZ_CP032694:c560841-560599 [Rhizobium jaguaris]
MDTAKIFWSGRSQAVRLPKEFRLDGEEVRIRRQGKAIILEPIVEDWDWLETVTGPVDQDFAEAATEQPAEQQSPELDIFK

Download         Length: 243 bp

>AT112160 NZ_CP032694:c560841-560599 [Rhizobium jaguaris]
ATGGACACCGCAAAAATCTTCTGGTCCGGCCGCTCGCAGGCCGTGCGTTTGCCAAAGGAATTCCGTCTCGACGGCGAAGA
AGTGCGCATCCGACGGCAGGGAAAAGCAATCATTCTGGAGCCGATCGTCGAAGATTGGGATTGGCTGGAGACCGTCACAG
GCCCCGTCGATCAGGACTTCGCAGAGGCCGCGACCGAACAGCCTGCAGAGCAGCAAAGCCCTGAGCTGGATATCTTCAAG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References