Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1035837..1036428 Replicon plasmid pRCCGE532d
Accession NZ_CP032690
Organism Rhizobium sp. CCGE532

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CCGE532_RS23835 Protein ID WP_120668525.1
Coordinates 1035837..1036142 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag CCGE532_RS23840 Protein ID WP_120668527.1
Coordinates 1036135..1036428 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE532_RS23815 1031371..1032534 - 1164 WP_120668517.1 DSD1 family PLP-dependent enzyme -
CCGE532_RS23820 1032548..1033495 - 948 WP_120668519.1 pyridoxal-phosphate dependent enzyme -
CCGE532_RS23825 1033507..1034697 - 1191 WP_120668521.1 aminotransferase class V-fold PLP-dependent enzyme -
CCGE532_RS23830 1034892..1035701 + 810 WP_120668523.1 IclR family transcriptional regulator -
CCGE532_RS23835 1035837..1036142 + 306 WP_120668525.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CCGE532_RS23840 1036135..1036428 + 294 WP_120668527.1 putative addiction module antidote protein Antitoxin
CCGE532_RS23845 1036994..1038286 + 1293 WP_120668529.1 NCS2 family permease -
CCGE532_RS23850 1038512..1038997 - 486 WP_120668531.1 ureidoglycolate lyase -
CCGE532_RS23855 1039041..1040495 - 1455 WP_120668533.1 allantoinase PuuE -
CCGE532_RS23860 1040656..1041021 + 366 WP_120668535.1 hydroxyisourate hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..1460443 1460443


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(3-93)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11245.98 Da        Isoelectric Point: 10.1358

>T112156 WP_120668525.1 NZ_CP032690:1035837-1036142 [Rhizobium sp. CCGE532]
MIELKQTATFAKWESRLQDKRAKTIIAARLMRLAEGLPGDVEPVGEGVSELRIHYGSGYRIYFQRRGNLLIVLLCGGNKG
SQARDIAAAKKLAKEWSAQDD

Download         Length: 306 bp

>T112156 NZ_CP032690:1035837-1036142 [Rhizobium sp. CCGE532]
ATGATTGAGTTAAAGCAAACCGCGACCTTCGCAAAATGGGAATCCCGCCTCCAAGACAAGCGAGCCAAAACCATTATCGC
GGCGCGACTGATGCGGTTGGCTGAAGGCTTGCCGGGCGACGTCGAACCGGTAGGCGAAGGCGTTAGCGAACTGCGGATTC
ACTACGGCTCTGGATATCGCATCTACTTCCAGCGGCGCGGAAATCTCCTGATCGTGTTGCTATGCGGCGGGAACAAAGGA
TCGCAAGCCCGCGACATCGCCGCCGCCAAGAAACTGGCTAAAGAATGGAGTGCACAAGATGACTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10423.88 Da        Isoelectric Point: 5.8373

>AT112156 WP_120668527.1 NZ_CP032690:1036135-1036428 [Rhizobium sp. CCGE532]
MTEKLTTYDPAAALVDDEEIAAFMADAFETGDAAYVAKALGVVARAKGMTEISRKTGLSREQLYRSFSERGNPTLKTTLA
VMRALGVDITAKPHTAQ

Download         Length: 294 bp

>AT112156 NZ_CP032690:1036135-1036428 [Rhizobium sp. CCGE532]
ATGACTGAAAAACTGACCACCTACGACCCTGCCGCCGCGCTGGTGGACGATGAAGAAATCGCCGCTTTCATGGCGGATGC
CTTTGAAACTGGCGACGCCGCCTATGTTGCCAAGGCGCTTGGTGTTGTCGCCCGGGCTAAAGGCATGACCGAAATATCTC
GCAAAACCGGGCTATCTCGGGAACAGCTCTACCGTTCGTTTAGCGAACGCGGAAACCCGACACTCAAAACGACACTTGCA
GTGATGCGCGCACTTGGCGTTGACATAACCGCCAAGCCCCATACCGCACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References