Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 280592..281175 Replicon chromosome
Accession NZ_CP032689
Organism Rhizobium sp. CCGE532

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CCGE532_RS01345 Protein ID WP_120662575.1
Coordinates 280592..280888 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CCGE532_RS01350 Protein ID WP_120662576.1
Coordinates 280885..281175 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE532_RS01315 275837..276613 - 777 WP_120662569.1 phosphonate C-P lyase system protein PhnK -
CCGE532_RS01320 276610..277536 - 927 WP_120662570.1 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ -
CCGE532_RS01325 277533..278642 - 1110 WP_120662571.1 carbon-phosphorus lyase complex subunit PhnI -
CCGE532_RS01330 278646..279272 - 627 WP_120662572.1 phosphonate C-P lyase system protein PhnH -
CCGE532_RS01335 279272..279748 - 477 WP_120662573.1 phosphonate C-P lyase system protein PhnG -
CCGE532_RS01340 279850..280584 + 735 WP_120662574.1 phosphonate metabolism transcriptional regulator PhnF -
CCGE532_RS01345 280592..280888 - 297 WP_120662575.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CCGE532_RS01350 280885..281175 - 291 WP_120662576.1 hypothetical protein Antitoxin
CCGE532_RS01355 281389..282024 - 636 WP_120662577.1 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase -
CCGE532_RS01360 282147..282971 - 825 WP_120662578.1 4-hydroxy-tetrahydrodipicolinate reductase -
CCGE532_RS01365 282986..284779 - 1794 WP_120662579.1 ABC transporter ATP-binding protein/permease -
CCGE532_RS01370 284991..286013 - 1023 WP_120662580.1 glucokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11196.90 Da        Isoelectric Point: 9.5301

>T112148 WP_120662575.1 NZ_CP032689:c280888-280592 [Rhizobium sp. CCGE532]
VKLAWTPEARADRRAIYTYIEAENASAAIALDELFAKRSKQLLAHPMAGRPGRISGTRELVVHRNYLLVYDLTDEMVRII
RILHAAQQWPPNDFQPIS

Download         Length: 297 bp

>T112148 NZ_CP032689:c280888-280592 [Rhizobium sp. CCGE532]
GTGAAACTTGCTTGGACTCCCGAGGCAAGGGCTGACCGACGCGCCATCTATACCTATATCGAGGCGGAGAACGCCTCCGC
GGCAATCGCTCTGGACGAGCTCTTCGCCAAACGGTCGAAACAGCTCCTTGCCCATCCAATGGCGGGCCGACCCGGCCGCA
TATCCGGGACACGAGAACTCGTCGTACATAGAAACTATCTGCTGGTTTACGACCTCACAGACGAGATGGTGCGCATAATC
CGTATTCTTCATGCAGCACAGCAATGGCCGCCGAACGATTTTCAGCCGATTTCCTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10752.82 Da        Isoelectric Point: 4.6413

>AT112148 WP_120662576.1 NZ_CP032689:c281175-280885 [Rhizobium sp. CCGE532]
MTDATFTFRVEEDLKAAFSEAAKAHDQTGAQLLRAFMRDYVKQQQNAAEYDAWFRQQVQAGLISANAGNLIPDDDVDAEF
AALREETRRKLSGHSS

Download         Length: 291 bp

>AT112148 NZ_CP032689:c281175-280885 [Rhizobium sp. CCGE532]
ATGACAGACGCGACATTTACTTTCCGGGTTGAAGAAGACCTGAAGGCGGCCTTCAGCGAAGCTGCGAAAGCGCACGATCA
AACCGGCGCGCAGTTGCTCCGGGCTTTTATGCGCGATTATGTGAAACAGCAGCAGAATGCGGCCGAATATGACGCCTGGT
TTCGCCAGCAGGTTCAGGCCGGTCTAATTTCCGCCAATGCTGGCAACCTCATTCCTGACGACGACGTAGACGCTGAATTT
GCAGCCTTGCGAGAGGAAACACGCCGCAAACTCAGCGGGCACTCTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References