Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1034838..1035429 Replicon plasmid pRCCGE531d
Accession NZ_CP032685
Organism Rhizobium sp. CCGE531

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CCGE531_RS24315 Protein ID WP_120668525.1
Coordinates 1034838..1035143 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag CCGE531_RS24320 Protein ID WP_120668527.1
Coordinates 1035136..1035429 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE531_RS24295 1030372..1031535 - 1164 WP_120668517.1 DSD1 family PLP-dependent enzyme -
CCGE531_RS24300 1031549..1032496 - 948 WP_120668519.1 pyridoxal-phosphate dependent enzyme -
CCGE531_RS24305 1032508..1033698 - 1191 WP_120668521.1 aminotransferase class V-fold PLP-dependent enzyme -
CCGE531_RS24310 1033893..1034702 + 810 WP_120668523.1 IclR family transcriptional regulator -
CCGE531_RS24315 1034838..1035143 + 306 WP_120668525.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CCGE531_RS24320 1035136..1035429 + 294 WP_120668527.1 putative addiction module antidote protein Antitoxin
CCGE531_RS24325 1035995..1037287 + 1293 WP_120668529.1 NCS2 family permease -
CCGE531_RS24330 1037513..1037998 - 486 WP_120668531.1 ureidoglycolate lyase -
CCGE531_RS24335 1038042..1039496 - 1455 WP_120668533.1 allantoinase PuuE -
CCGE531_RS24340 1039657..1040022 + 366 WP_120668535.1 hydroxyisourate hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..1460465 1460465


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(3-93)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11245.98 Da        Isoelectric Point: 10.1358

>T112145 WP_120668525.1 NZ_CP032685:1034838-1035143 [Rhizobium sp. CCGE531]
MIELKQTATFAKWESRLQDKRAKTIIAARLMRLAEGLPGDVEPVGEGVSELRIHYGSGYRIYFQRRGNLLIVLLCGGNKG
SQARDIAAAKKLAKEWSAQDD

Download         Length: 306 bp

>T112145 NZ_CP032685:1034838-1035143 [Rhizobium sp. CCGE531]
ATGATTGAGTTAAAGCAAACCGCGACCTTCGCAAAATGGGAATCCCGCCTCCAAGACAAGCGAGCCAAAACCATTATCGC
GGCGCGACTGATGCGGTTGGCTGAAGGCTTGCCGGGCGACGTCGAACCGGTAGGCGAAGGCGTTAGCGAACTGCGGATTC
ACTACGGCTCTGGATATCGCATCTACTTCCAGCGGCGCGGAAATCTCCTGATCGTGTTGCTATGCGGCGGGAACAAAGGA
TCGCAAGCCCGCGACATCGCCGCCGCCAAGAAACTGGCTAAAGAATGGAGTGCACAAGATGACTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10423.88 Da        Isoelectric Point: 5.8373

>AT112145 WP_120668527.1 NZ_CP032685:1035136-1035429 [Rhizobium sp. CCGE531]
MTEKLTTYDPAAALVDDEEIAAFMADAFETGDAAYVAKALGVVARAKGMTEISRKTGLSREQLYRSFSERGNPTLKTTLA
VMRALGVDITAKPHTAQ

Download         Length: 294 bp

>AT112145 NZ_CP032685:1035136-1035429 [Rhizobium sp. CCGE531]
ATGACTGAAAAACTGACCACCTACGACCCTGCCGCCGCGCTGGTGGACGATGAAGAAATCGCCGCTTTCATGGCGGATGC
CTTTGAAACTGGCGACGCCGCCTATGTTGCCAAGGCGCTTGGTGTTGTCGCCCGGGCTAAAGGCATGACCGAAATATCTC
GCAAAACCGGGCTATCTCGGGAACAGCTCTACCGTTCGTTTAGCGAACGCGGAAACCCGACACTCAAAACGACACTTGCA
GTGATGCGCGCACTTGGCGTTGACATAACCGCCAAGCCCCATACCGCACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References