Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3656934..3657468 Replicon chromosome
Accession NZ_CP032684
Organism Rhizobium sp. CCGE531

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CCGE531_RS17825 Protein ID WP_120665705.1
Coordinates 3656934..3657236 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CCGE531_RS17830 Protein ID WP_120665708.1
Coordinates 3657226..3657468 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE531_RS17805 3652053..3654116 - 2064 WP_120665696.1 M3 family metallopeptidase -
CCGE531_RS17810 3654229..3654870 - 642 WP_120665699.1 LysE family translocator -
CCGE531_RS17815 3655032..3655514 + 483 WP_120665702.1 MarR family winged helix-turn-helix transcriptional regulator -
CCGE531_RS17820 3655590..3656813 - 1224 WP_120666927.1 argininosuccinate synthase -
CCGE531_RS17825 3656934..3657236 - 303 WP_120665705.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CCGE531_RS17830 3657226..3657468 - 243 WP_120665708.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CCGE531_RS17835 3657553..3658407 + 855 WP_120665711.1 SDR family NAD(P)-dependent oxidoreductase -
CCGE531_RS17840 3658476..3659117 + 642 WP_120665714.1 LysE family translocator -
CCGE531_RS17845 3659101..3659529 - 429 WP_120665717.1 hypothetical protein -
CCGE531_RS17850 3659535..3660770 - 1236 WP_120666929.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
CCGE531_RS17855 3661056..3661619 - 564 WP_120665720.1 hypothetical protein -
CCGE531_RS17860 3661952..3662341 - 390 WP_120665723.1 DUF1232 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3576251..3693822 117571


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-95)

Antitoxin

Antitoxin ParD

(5-71)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11346.11 Da        Isoelectric Point: 10.2742

>T112143 WP_120665705.1 NZ_CP032684:c3657236-3656934 [Rhizobium sp. CCGE531]
MSAKSRSYKLLPKARQDLDAIWRYTFETWSLQQANTYYNELIGCFPELAAGTARGRKVSGIKPDYLALASGSHFIIYKDG
AQTVTIIRILHRRMNIGAHL

Download         Length: 303 bp

>T112143 NZ_CP032684:c3657236-3656934 [Rhizobium sp. CCGE531]
ATGTCCGCTAAAAGCCGATCCTATAAGCTCTTGCCGAAAGCGCGACAGGATTTGGATGCTATTTGGCGATACACATTTGA
GACTTGGTCTCTTCAGCAGGCAAATACTTACTACAACGAGCTGATTGGTTGTTTTCCGGAATTGGCAGCTGGAACCGCCC
GGGGTCGCAAAGTTAGCGGTATCAAACCTGATTATCTTGCTCTGGCCTCCGGCTCACATTTCATCATCTACAAAGATGGC
GCTCAAACGGTCACAATCATCCGCATCCTGCATCGGCGAATGAATATCGGTGCTCATCTCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8755.77 Da        Isoelectric Point: 4.2919

>AT112143 WP_120665708.1 NZ_CP032684:c3657468-3657226 [Rhizobium sp. CCGE531]
VTKHVSIDIDEQMAAFIGEQISHGNYASPSEVIDAALKLLRSRAEIEAIAIAIAEGEASGEPEEFDGEAFLTELHRKYVR

Download         Length: 243 bp

>AT112143 NZ_CP032684:c3657468-3657226 [Rhizobium sp. CCGE531]
GTGACAAAGCATGTGTCCATAGACATCGACGAGCAGATGGCGGCATTCATCGGCGAGCAGATCAGCCACGGCAACTACGC
TTCGCCGAGCGAGGTCATTGACGCGGCACTGAAACTATTGCGCAGCCGGGCGGAAATAGAAGCGATTGCGATCGCCATTG
CCGAGGGCGAGGCCTCGGGAGAGCCGGAGGAGTTTGACGGTGAGGCGTTTCTGACGGAGCTGCACCGCAAATATGTCCGC
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References