Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2987405..2988069 Replicon chromosome
Accession NZ_CP032684
Organism Rhizobium sp. CCGE531

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CCGE531_RS14600 Protein ID WP_120664815.1
Coordinates 2987659..2988069 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CCGE531_RS14595 Protein ID WP_120664814.1
Coordinates 2987405..2987659 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE531_RS14565 2982662..2983390 - 729 WP_120666847.1 class I SAM-dependent methyltransferase -
CCGE531_RS14570 2983460..2983849 - 390 WP_120664811.1 RidA family protein -
CCGE531_RS14575 2983911..2984807 - 897 WP_120666849.1 DMT family transporter -
CCGE531_RS14580 2985157..2985582 + 426 WP_120666850.1 hypothetical protein -
CCGE531_RS14585 2985623..2986234 - 612 WP_120664812.1 alpha/beta hydrolase -
CCGE531_RS14590 2986250..2987182 - 933 WP_120664813.1 VOC family protein -
CCGE531_RS14595 2987405..2987659 + 255 WP_120664814.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CCGE531_RS14600 2987659..2988069 + 411 WP_120664815.1 type II toxin-antitoxin system VapC family toxin Toxin
CCGE531_RS14605 2988170..2988868 - 699 WP_120664816.1 uracil-DNA glycosylase -
CCGE531_RS14610 2989140..2990828 - 1689 WP_120664817.1 AIPR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-68)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15108.20 Da        Isoelectric Point: 6.8810

>T112142 WP_120664815.1 NZ_CP032684:2987659-2988069 [Rhizobium sp. CCGE531]
MYLVDTNVISEVRRGNSQAVAWLRSIDPSTVYLSVITLGEIMRGIALKRKSDPRAAAHLEEWLRKIRHDHGNRILAITDQ
IAVEWGRIAAQRPRGDADGLIAATAIVHDLIVVTRNVGDFDDTGASIINPWDQAPY

Download         Length: 411 bp

>T112142 NZ_CP032684:2987659-2988069 [Rhizobium sp. CCGE531]
ATGTATCTGGTCGATACCAACGTCATCTCGGAAGTTCGGCGCGGTAATTCCCAGGCGGTTGCCTGGCTGCGCTCAATCGA
TCCCTCCACCGTTTATCTGAGTGTCATCACACTTGGAGAAATCATGCGCGGGATTGCGCTGAAGCGAAAATCGGACCCAC
GCGCCGCAGCGCATCTGGAAGAATGGCTGCGCAAGATCCGGCACGATCATGGCAATCGCATCCTTGCCATTACCGATCAG
ATTGCGGTCGAATGGGGACGTATCGCCGCACAGCGTCCGCGCGGTGATGCCGATGGATTAATCGCGGCAACGGCGATCGT
TCATGACCTCATCGTCGTCACTCGCAACGTCGGCGATTTCGACGACACCGGCGCTTCAATCATCAACCCCTGGGACCAGG
CGCCTTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9173.34 Da        Isoelectric Point: 4.7265

>AT112142 WP_120664814.1 NZ_CP032684:2987405-2987659 [Rhizobium sp. CCGE531]
MNWPLQDAKNQFSKVVQKARSEGPQIVTLRGERAAVVLSAEDYDALLAGKPSLADDLLSGPAWDDEMADAVSKRSKTPSR
DVLF

Download         Length: 255 bp

>AT112142 NZ_CP032684:2987405-2987659 [Rhizobium sp. CCGE531]
ATGAATTGGCCATTGCAGGATGCGAAGAACCAGTTTTCAAAAGTCGTGCAGAAAGCGCGCAGTGAGGGACCGCAAATCGT
CACCTTGCGCGGCGAACGTGCGGCTGTCGTCCTGTCTGCCGAAGACTATGATGCTCTCCTGGCCGGCAAACCGAGCCTTG
CCGATGACTTGCTATCCGGACCGGCATGGGATGACGAAATGGCTGATGCCGTATCGAAGCGCAGCAAAACGCCAAGCCGG
GATGTCCTTTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References