Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1923071..1923342 Replicon chromosome
Accession NZ_CP032679
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1923109..1923212 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1923071..1923342 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7U33_RS09420 1920228..1921667 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
D7U33_RS09425 1921785..1922021 + 237 WP_001295499.1 DUF1480 family protein -
D7U33_RS09430 1922126..1922317 + 192 WP_000457842.1 YebW family protein -
D7U33_RS09435 1922318..1922974 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1923071..1923342 + 272 - - Antitoxin
- 1923109..1923212 - 104 - - Toxin
D7U33_RS09440 1923370..1923711 - 342 WP_000976476.1 YebY family protein -
D7U33_RS09445 1923724..1924596 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
D7U33_RS09450 1924600..1924974 - 375 WP_000168747.1 CopC domain-containing protein YobA -
D7U33_RS09455 1925113..1925343 + 231 WP_000916763.1 DNA polymerase III subunit theta -
D7U33_RS09460 1925445..1926101 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
D7U33_RS09465 1926125..1926787 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112108 NZ_CP032679:c1923212-1923109 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT112108 NZ_CP032679:1923071-1923342 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References