Detailed information of TA system TA112088

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 4005332..4005807
• Replicon: chromosome
• Accession: NZ_CP032674
• Organism: Xanthobacter sp. YC-JY1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: D7006_RS18745
• Protein ID: WP_237354111.1
• Coordinates: 4005332..4005541 (-)
• Length: 70 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: D7006_RS18750
• Protein ID: WP_237354112.1
• Coordinates: 4005529..4005807 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D7006_RS18735	4001409..4002800	-	1392	WP_237354109.1	hypothetical protein	-
D7006_RS18740 (D7006_18600)	4002886..4003791	-	906	WP_237354110.1	hypothetical protein	-
D7006_RS18745 (D7006_18605)	4005332..4005541	-	210	WP_237354111.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
D7006_RS18750 (D7006_18610)	4005529..4005807	-	279	WP_237354112.1	CopG family ribbon-helix-helix protein	Antitoxin
D7006_RS18760 (D7006_18620)	4006520..4008019	-	1500	WP_237354113.1	tripartite tricarboxylate transporter permease	-
D7006_RS18765 (D7006_18625)	4008030..4008491	-	462	WP_169124072.1	tripartite tricarboxylate transporter TctB family protein	-
D7006_RS18770 (D7006_18630)	4008702..4009676	-	975	WP_237354114.1	tripartite tricarboxylate transporter substrate binding protein BugD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-53)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 70 a.a.
• Molecular weight: 7437.54 Da
• Isoelectric Point: 11.9891

>T112088 WP_237354111.1 NZ_CP032674:c4005541-4005332 [Xanthobacter sp. YC-JY1]
MPQVRFSPAAIRDLERLRAFLSPKNPAAAKRAGEAIIDGVRALGTHPHMGPDDRRSSRAVSGLAHPVWG

Nucleotide

• Length: 210 bp

>T112088 NZ_CP032674:c4005541-4005332 [Xanthobacter sp. YC-JY1]
ATGCCGCAAGTGAGATTTTCGCCAGCTGCGATCCGTGACCTTGAGCGGCTACGGGCGTTTCTAAGCCCCAAGAATCCTGC
CGCTGCGAAAAGAGCCGGCGAGGCCATCATAGACGGCGTTCGTGCACTCGGCACACATCCTCACATGGGGCCGGACGATC
GACGGTCTTCCCGAGCAGTTTCGGGACTGGCTCATCCCGTTTGGGGATAG

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10699.01 Da
• Isoelectric Point: 6.4734

>AT112088 WP_237354112.1 NZ_CP032674:c4005807-4005529 [Xanthobacter sp. YC-JY1]
MASATSIKLDDELKGRIQRLAEVRRRSSHWIMREAIAQYVEREEKREALRQDSLKAWDEFQATGVHATAEDVEKWLSSWG
TESELPAPQCRK

Nucleotide

• Length: 279 bp

>AT112088 NZ_CP032674:c4005807-4005529 [Xanthobacter sp. YC-JY1]
ATGGCATCGGCAACATCCATCAAACTCGACGATGAGTTGAAAGGGCGCATCCAGCGTCTCGCGGAAGTTCGCCGTCGCTC
CTCCCATTGGATCATGCGGGAGGCGATCGCGCAGTACGTGGAGCGCGAGGAAAAGCGCGAGGCGCTGCGACAGGACTCCC
TCAAGGCATGGGACGAGTTTCAGGCAACGGGCGTGCATGCCACAGCCGAGGATGTCGAGAAGTGGTTGTCGAGTTGGGGA
ACTGAAAGCGAGCTGCCGGCACCTCAATGCCGCAAGTGA