Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2671802..2672358 Replicon chromosome
Accession NZ_CP032674
Organism Xanthobacter sp. YC-JY1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D7006_RS12465 Protein ID WP_237356810.1
Coordinates 2671993..2672358 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D7006_RS12460 Protein ID WP_169120256.1
Coordinates 2671802..2671996 (+) Length 65 a.a.

Genomic Context


D7006_RS12445D7006_RS12460D7006_RS12465D7006_RS12470D7006_RS12475D7006_RS12485D7006_RS12490D7006_RS12440D7006_RS12450D7006_RS12455D7006_RS12480
Location: 2668724..2669785 (1062 bp)
Type: Others
Protein ID: WP_169120260.1
Location: 2671802..2671996 (195 bp)
Type: Antitoxin
Protein ID: WP_169120256.1
Location: 2671993..2672358 (366 bp)
Type: Toxin
Protein ID: WP_237356810.1
Location: 2672400..2672918 (519 bp)
Type: Others
Protein ID: WP_237356811.1
Location: 2673096..2674031 (936 bp)
Type: Others
Protein ID: WP_169120239.1
Location: 2674771..2675718 (948 bp)
Type: Others
Protein ID: WP_169120235.1
Location: 2675711..2677057 (1347 bp)
Type: Others
Protein ID: WP_237356813.1
Location: 2666973..2668463 (1491 bp)
Type: Others
Protein ID: WP_169120262.1
Location: 2669865..2671349 (1485 bp)
Type: Others
Protein ID: WP_237356809.1
Location: 2671346..2671633 (288 bp)
Type: Others
Protein ID: WP_024278942.1
Location: 2674100..2674525 (426 bp)
Type: Others
Protein ID: WP_237356812.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D7006_RS12440 (D7006_12355)2666973..2668463-1491WP_169120262.1Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB-
D7006_RS12445 (D7006_12360)2668724..2669785+1062WP_169120260.1glycosyltransferase family 2 protein-
D7006_RS12450 (D7006_12365)2669865..2671349-1485WP_237356809.1Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA-
D7006_RS12455 (D7006_12370)2671346..2671633-288WP_024278942.1Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC-
D7006_RS12460 (D7006_12375)2671802..2671996+195WP_169120256.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
D7006_RS12465 (D7006_12380)2671993..2672358+366WP_237356810.1type II toxin-antitoxin system VapC family toxinToxin
D7006_RS12470 (D7006_12385)2672400..2672918+519WP_237356811.1Holliday junction resolvase RuvX-
D7006_RS12475 (D7006_12390)2673096..2674031+936WP_169120239.1AEC family transporter-
D7006_RS12480 (D7006_12395)2674100..2674525-426WP_237356812.1hypothetical protein-
D7006_RS12485 (D7006_12400)2674771..2675718+948WP_169120235.1aspartate carbamoyltransferase catalytic subunit-
D7006_RS12490 (D7006_12405)2675711..2677057+1347WP_237356813.1dihydroorotase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-113)

Antitoxin

(1-44)


Sequences


Toxin        


Download         Length: 122 a.a.        Molecular weight: 13182.35 Da        Isoelectric Point: 5.1055

>T112087 WP_237356810.1 NZ_CP032674:2671993-2672358 [Xanthobacter sp. YC-JY1]
MILVDTSIWIDHFRQCDPRLQQVLADGSVMSHPFVIGELALGNLRQREVILDAIAALPQAIIAEPAEVLGLITTESLHGR
GIGYVDAHLIASVRLTPEAVLWTRDRRLAAVAEKLGIALEA

Download         Length: 366 bp

>T112087 NZ_CP032674:2671993-2672358 [Xanthobacter sp. YC-JY1]
ATGATTCTGGTCGATACGTCCATCTGGATCGATCATTTTCGCCAATGCGATCCGAGGCTGCAGCAGGTGCTGGCGGACGG
CTCCGTGATGTCGCATCCCTTCGTGATCGGCGAACTCGCACTGGGGAACCTGCGTCAGCGGGAGGTCATCCTGGATGCCA
TCGCCGCCTTGCCGCAGGCGATCATTGCCGAACCGGCCGAAGTGCTCGGCCTCATAACGACCGAGTCGCTCCATGGCCGA
GGGATTGGATATGTCGACGCGCACTTGATTGCGTCGGTTCGATTGACGCCGGAAGCGGTTTTGTGGACGCGCGACAGGCG
GTTGGCAGCTGTTGCGGAAAAACTGGGAATTGCGCTTGAGGCGTGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7126.27 Da        Isoelectric Point: 10.6723

>AT112087 WP_169120256.1 NZ_CP032674:2671802-2671996 [Xanthobacter sp. YC-JY1]
MRTTLAIDDELLARAQALTGMTEKSALVREALKALIARESALRLARLGGSEPQLEPIRRRRPDE

Download         Length: 195 bp

>AT112087 NZ_CP032674:2671802-2671996 [Xanthobacter sp. YC-JY1]
ATGCGAACCACCCTCGCCATAGACGACGAGCTTCTCGCAAGAGCACAGGCATTGACCGGCATGACAGAGAAGTCGGCTCT
CGTGCGCGAGGCACTCAAAGCGCTGATCGCCCGCGAGAGCGCATTGCGTCTCGCCCGTCTCGGCGGGAGCGAGCCCCAGC
TTGAACCGATCCGTAGACGCCGGCCCGACGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References