Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4844477..4845002 Replicon chromosome
Accession NZ_CP032631
Organism Pseudomonas syringae pv. actinidiae str. Shaanxi_M228

Toxin (Protein)


Gene name relE Uniprot ID A0A0K8M609
Locus tag CN228_RS23475 Protein ID WP_017684329.1
Coordinates 4844712..4845002 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0K8M645
Locus tag CN228_RS23470 Protein ID WP_017684328.1
Coordinates 4844477..4844722 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CN228_RS23465 4840393..4844304 - 3912 WP_020365655.1 ATP-dependent RNA helicase HrpA -
CN228_RS23470 4844477..4844722 + 246 WP_017684328.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CN228_RS23475 4844712..4845002 + 291 WP_017684329.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CN228_RS23480 4845129..4846820 - 1692 WP_003382607.1 long-chain-fatty-acid--CoA ligase FadD1 -
CN228_RS23485 4847176..4848864 - 1689 WP_017684330.1 long-chain-fatty-acid--CoA ligase FadD2 -
CN228_RS23495 4849260..4849730 + 471 WP_003382605.1 MaoC family dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11019.86 Da        Isoelectric Point: 10.4180

>T112036 WP_017684329.1 NZ_CP032631:4844712-4845002 [Pseudomonas syringae pv. actinidiae str. Shaanxi_M228]
MTFKLEFLPSALKEWKKLGHTVSAQLKKKLLERLELPRNAGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGK
RERGDIYDSAKDRLSP

Download         Length: 291 bp

>T112036 NZ_CP032631:4844712-4845002 [Pseudomonas syringae pv. actinidiae str. Shaanxi_M228]
TTGACCTTTAAGCTCGAGTTTCTGCCTTCAGCCCTGAAAGAGTGGAAAAAACTGGGGCATACCGTTAGTGCTCAACTCAA
GAAAAAGCTTTTGGAGCGGCTCGAATTACCTCGAAATGCGGGCGATGCGCTGCATGGCATGCCCGATCACTACAAAATCA
AGTTGCGCAGTGCTGGTTACAGACTGGTTTACCGGGTGGAAGATGATCGGGTAGTAGTGACCGTCGTCGCTGTAGGCAAG
CGCGAACGAGGCGATATCTACGATTCAGCCAAGGACAGGCTGTCTCCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8860.38 Da        Isoelectric Point: 4.9721

>AT112036 WP_017684328.1 NZ_CP032631:4844477-4844722 [Pseudomonas syringae pv. actinidiae str. Shaanxi_M228]
MQNIFADIAVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMKRLDDLDLADLIKARQHEKPVSVDILD
L

Download         Length: 246 bp

>AT112036 NZ_CP032631:4844477-4844722 [Pseudomonas syringae pv. actinidiae str. Shaanxi_M228]
ATGCAAAATATCTTTGCGGACATCGCGGTCAGCGTCTCTGAACTGAAGAAAAACCCGTCAGCCGTCCTGAGCGGCGCACA
AGGCTTGCCCGTCGCAGTACTCAATCACAATAAAGTCATGGGCTACATGGTGCCTGCCGAGGTGTTTGAAGCAATGATGA
AGCGCCTTGATGACCTCGATCTGGCCGACCTGATCAAAGCCAGGCAACATGAAAAGCCGGTATCGGTAGATATACTTGAC
CTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M609

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M645

References