Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3201508..3202061 Replicon chromosome
Accession NZ_CP032624
Organism Gryllotalpicola protaetiae strain 2DFW10M-5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D7I44_RS15590 Protein ID WP_120790336.1
Coordinates 3201789..3202061 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D7I44_RS15585 Protein ID WP_120790335.1
Coordinates 3201508..3201792 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7I44_RS15560 3197072..3198757 + 1686 WP_120790332.1 sodium:proton antiporter -
D7I44_RS15565 3198754..3199230 - 477 WP_120791003.1 GNAT family N-acetyltransferase -
D7I44_RS15570 3199289..3199987 - 699 WP_120790333.1 SDR family oxidoreductase -
D7I44_RS15575 3200030..3200761 + 732 WP_120790334.1 SDR family NAD(P)-dependent oxidoreductase -
D7I44_RS15580 3200862..3201284 + 423 WP_120791004.1 DUF1801 domain-containing protein -
D7I44_RS15585 3201508..3201792 + 285 WP_120790335.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
D7I44_RS15590 3201789..3202061 + 273 WP_120790336.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D7I44_RS15595 3202227..3202622 + 396 WP_120790337.1 VOC family protein -
D7I44_RS15600 3202632..3203453 + 822 WP_120790338.1 LLM class F420-dependent oxidoreductase -
D7I44_RS15605 3203472..3203870 - 399 WP_120790339.1 type II toxin-antitoxin system VapC family toxin -
D7I44_RS15610 3203874..3204128 - 255 WP_120790340.1 type II toxin-antitoxin system VapB family antitoxin -
D7I44_RS15615 3204316..3204690 + 375 WP_120790341.1 VOC family protein -
D7I44_RS15620 3204930..3206348 + 1419 WP_120791005.1 MFS transporter -
D7I44_RS15625 3206383..3207057 + 675 WP_120790342.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(11-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10407.05 Da        Isoelectric Point: 10.3955

>T112028 WP_120790336.1 NZ_CP032624:3201789-3202061 [Gryllotalpicola protaetiae]
VSDLYEVVFTRAARRALEQDLPEKVAAAAFEFIMGALRENPHRVGKPLREPLAPLYSARRGEYRVLYRIVGDRLLVEVVS
IAHRRDAYRR

Download         Length: 273 bp

>T112028 NZ_CP032624:3201789-3202061 [Gryllotalpicola protaetiae]
GTGAGCGACCTCTACGAGGTCGTCTTCACGCGTGCAGCCCGGCGCGCGTTGGAACAGGACTTGCCAGAGAAAGTGGCGGC
GGCGGCGTTCGAGTTCATCATGGGCGCTCTGCGCGAAAACCCACACCGGGTGGGCAAGCCCTTAAGGGAACCGTTGGCAC
CCCTGTACTCGGCCCGCCGCGGCGAGTACCGCGTGCTCTACCGGATCGTTGGAGACCGGCTTCTCGTCGAGGTCGTCTCA
ATCGCTCACCGTCGCGACGCCTATCGCCGTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10217.47 Da        Isoelectric Point: 4.4179

>AT112028 WP_120790335.1 NZ_CP032624:3201508-3201792 [Gryllotalpicola protaetiae]
MTTLSVADARANFSKLIESAITTHERFEVTRNGARAAVLLSADDYDALLETVDILSRPDEVEAIRQGLADLVAGEVSTAE
EVREAMIARGRLSR

Download         Length: 285 bp

>AT112028 NZ_CP032624:3201508-3201792 [Gryllotalpicola protaetiae]
ATGACAACGCTTTCTGTAGCGGATGCCCGCGCGAACTTCTCCAAGCTGATCGAGTCGGCCATCACCACGCATGAGCGTTT
CGAGGTGACCCGTAACGGCGCCCGCGCCGCCGTGCTGCTGAGCGCCGACGACTATGACGCACTGTTGGAAACCGTCGATA
TCCTCAGCCGTCCCGATGAGGTCGAGGCGATCCGCCAGGGACTGGCCGATCTGGTCGCGGGAGAGGTCTCGACCGCAGAG
GAAGTGCGGGAAGCGATGATCGCGCGCGGTCGGCTTTCTCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References