Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK(toxin)
Location 1862537..1863123 Replicon chromosome
Accession NZ_CP032624
Organism Gryllotalpicola protaetiae strain 2DFW10M-5

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag D7I44_RS09180 Protein ID WP_120789222.1
Coordinates 1862537..1862881 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag D7I44_RS09185 Protein ID WP_120789223.1
Coordinates 1862878..1863123 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7I44_RS09160 1858160..1859293 + 1134 WP_120789219.1 bifunctional 2-methylcitrate synthase/citrate synthase -
D7I44_RS09165 1859297..1861369 - 2073 WP_120790875.1 glycoside hydrolase family 3 protein -
D7I44_RS09170 1861595..1862206 + 612 WP_120789220.1 TetR/AcrR family transcriptional regulator -
D7I44_RS09175 1862179..1862502 - 324 WP_120789221.1 hypothetical protein -
D7I44_RS09180 1862537..1862881 - 345 WP_120789222.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
D7I44_RS09185 1862878..1863123 - 246 WP_120789223.1 ribbon-helix-helix protein, CopG family Antitoxin
D7I44_RS09190 1863281..1864234 + 954 WP_120789224.1 DNA-3-methyladenine glycosylase -
D7I44_RS09195 1864251..1867973 + 3723 WP_120789225.1 proline dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-33)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12010.90 Da        Isoelectric Point: 4.9004

>T112027 WP_120789222.1 NZ_CP032624:c1862881-1862537 [Gryllotalpicola protaetiae]
VTARGDVVWVDFGQPRGSQPAKVRPAVIFQDDWLLATAISTVQIVPLTSNLALEAFPGNVLVPAAASGLDKDSVALVTQL
GPVSREFLQPYAVGRLPAYLMNELGAGVRLVTGI

Download         Length: 345 bp

>T112027 NZ_CP032624:c1862881-1862537 [Gryllotalpicola protaetiae]
GTGACCGCACGCGGCGATGTGGTCTGGGTGGACTTCGGCCAGCCACGCGGATCACAGCCGGCAAAGGTCCGTCCGGCCGT
GATCTTCCAAGATGACTGGTTGCTGGCGACAGCGATCAGCACGGTGCAGATCGTTCCGCTGACGTCGAACCTCGCTCTCG
AAGCATTTCCCGGCAACGTGCTCGTGCCGGCCGCAGCGTCTGGGCTCGACAAGGATTCCGTCGCTCTGGTCACACAGCTC
GGGCCTGTCAGCCGTGAATTCCTGCAGCCATACGCTGTCGGGCGACTCCCGGCATACCTGATGAACGAACTCGGTGCCGG
TGTGCGCTTGGTCACCGGCATCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8952.95 Da        Isoelectric Point: 4.7872

>AT112027 WP_120789223.1 NZ_CP032624:c1863123-1862878 [Gryllotalpicola protaetiae]
MKTAISVPDDDFQRFERIAARNGMSRSEFYRRAGAKLADELEGASRLTAIADSVLTRVGRASDADLFLSEAQRVIESGSD
W

Download         Length: 246 bp

>AT112027 NZ_CP032624:c1863123-1862878 [Gryllotalpicola protaetiae]
ATGAAGACGGCGATTTCGGTTCCGGACGACGACTTCCAGCGATTCGAGCGCATTGCGGCACGCAACGGGATGAGTCGTTC
TGAGTTCTATCGACGCGCAGGCGCCAAGCTGGCCGACGAGCTCGAAGGCGCCAGCCGCCTGACGGCCATCGCCGACTCGG
TTCTGACTCGGGTCGGCCGAGCGTCTGACGCCGATCTCTTCCTCAGCGAGGCGCAGCGCGTCATCGAGTCCGGAAGCGAC
TGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References