Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 4360357..4361082 Replicon chromosome
Accession NZ_CP032619
Organism Pectobacterium carotovorum strain HG-49

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag D7Z95_RS19535 Protein ID WP_181838212.1
Coordinates 4360762..4361082 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag D7Z95_RS19530 Protein ID WP_205946720.1
Coordinates 4360357..4360692 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7Z95_RS19505 4356382..4357203 + 822 WP_264041097.1 hypothetical protein -
D7Z95_RS19510 4357277..4358152 + 876 WP_205568487.1 50S ribosome-binding GTPase -
D7Z95_RS19515 4358450..4359004 + 555 WP_094431875.1 hypothetical protein -
D7Z95_RS19520 4359033..4359638 + 606 WP_205568485.1 hypothetical protein -
D7Z95_RS19525 4359844..4360317 + 474 WP_205568484.1 DNA repair protein RadC -
D7Z95_RS19530 4360357..4360692 + 336 WP_205946720.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
D7Z95_RS19535 4360762..4361082 + 321 WP_181838212.1 TA system toxin CbtA family protein Toxin
D7Z95_RS19540 4361200..4362033 + 834 WP_205948188.1 DUF4942 domain-containing protein -
D7Z95_RS19545 4362243..4362353 + 111 Protein_3806 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
D7Z95_RS19550 4362987..4363343 - 357 WP_205946718.1 hypothetical protein -
D7Z95_RS19555 4363571..4363789 - 219 WP_180777774.1 KTSC domain-containing protein -
D7Z95_RS19560 4364062..4365477 - 1416 WP_205946717.1 diguanylate cyclase -
D7Z95_RS19565 4365688..4365891 + 204 WP_015840819.1 protein DsrB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12098.83 Da        Isoelectric Point: 4.6104

>T112021 WP_181838212.1 NZ_CP032619:4360762-4361082 [Pectobacterium carotovorum]
MQTIPEIPSREEQSCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDILRARRATGLLKA

Download         Length: 321 bp

>T112021 NZ_CP032619:4360762-4361082 [Pectobacterium carotovorum]
ATGCAAACCATACCGGAAATCCCGTCACGGGAGGAGCAATCCTGCCCGTCACCTATAGCCGTCTGGCAGCAACTGCTTAC
CTACCTGTTAGAAAAGCACTACGGCCTGACGCTGAACGACACACCGTTCTGTGAGGAAAACGTCATTCAGGCGCATATCG
ATGCTGGCGTCACGCTGGTCAATGCCGTCAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGATCGCGACGGTTTT
AACTGGCAGGAGCAATCACCGTTTCTCACCGCCGTTGATATTCTCCGTGCCAGACGCGCTACCGGCTTGCTTAAAGCATA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12482.15 Da        Isoelectric Point: 5.1279

>AT112021 WP_205946720.1 NZ_CP032619:4360357-4360692 [Pectobacterium carotovorum]
MPSSETPEWGLKRAVMPQFGARLVQEGHYLHYLADRASIVGTFSETEARHLERCFPEMIKQLEQKLCSGELNPRQQGCIT
LHCNEWTCEADTLGSFGYVYIAIYPSAAAAE

Download         Length: 336 bp

>AT112021 NZ_CP032619:4360357-4360692 [Pectobacterium carotovorum]
ATGCCATCATCGGAGACCCCGGAATGGGGACTAAAACGTGCCGTCATGCCGCAATTCGGAGCCAGGCTGGTGCAGGAAGG
TCACTATCTGCATTATCTGGCAGACCGGGCCAGCATTGTCGGTACGTTTAGCGAAACGGAAGCCCGTCATCTGGAACGCT
GCTTCCCGGAGATGATTAAGCAGTTGGAACAAAAACTGTGCTCGGGTGAGTTGAATCCCCGCCAGCAGGGCTGCATCACG
CTGCATTGCAACGAATGGACCTGTGAAGCCGATACGCTGGGTAGTTTTGGTTACGTGTATATTGCTATTTATCCCTCTGC
TGCGGCAGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References