Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2611201..2611736 Replicon chromosome
Accession NZ_CP032619
Organism Pectobacterium carotovorum strain HG-49

Toxin (Protein)


Gene name relE Uniprot ID A0A7V8Q6Q4
Locus tag D7Z95_RS11755 Protein ID WP_039284929.1
Coordinates 2611201..2611488 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag D7Z95_RS11760 Protein ID WP_010281712.1
Coordinates 2611485..2611736 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7Z95_RS11740 2607688..2608416 - 729 WP_043881851.1 DUF1266 domain-containing protein -
D7Z95_RS11745 2608770..2609612 + 843 WP_015842271.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
D7Z95_RS11750 2609741..2611093 + 1353 WP_181848045.1 glutathione-disulfide reductase -
D7Z95_RS11755 2611201..2611488 - 288 WP_039284929.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D7Z95_RS11760 2611485..2611736 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
D7Z95_RS11765 2611991..2612896 + 906 WP_205947289.1 siderophore-interacting protein -
D7Z95_RS11770 2612931..2613686 - 756 WP_205947288.1 thiol:disulfide interchange protein DsbG -
D7Z95_RS11775 2613756..2614460 - 705 WP_205947287.1 SMI1/KNR4 family protein -
D7Z95_RS11780 2614642..2615265 + 624 WP_194431385.1 LysE family translocator -
D7Z95_RS11785 2615308..2616441 - 1134 WP_205947286.1 alkylhydroperoxidase domain protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11088.18 Da        Isoelectric Point: 10.3527

>T112012 WP_039284929.1 NZ_CP032619:c2611488-2611201 [Pectobacterium carotovorum]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDILIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T112012 NZ_CP032619:c2611488-2611201 [Pectobacterium carotovorum]
ATGAGCTATAGCGTCAAATTCAGGGAAGATGCGCTGAAAGAATGGCTCAAGCTCGATAAAACCATCCAACAGCAATTTGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCTCATATTCCTTCGGCAAAGTTACGGGGGATGAAGGACTGCTACAAAATAA
AGCTCCGAGCATCAGGCTTTCGTTTGGTTTATGAAGTCATTGACGACATCTTGATTATTGCCGTGGTGGCGGTAGGTAAA
CGTGAACGCAGCGGTGTTTATCATCTGGCGAGTGAGCGAATGAGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT112012 WP_010281712.1 NZ_CP032619:c2611736-2611485 [Pectobacterium carotovorum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT112012 NZ_CP032619:c2611736-2611485 [Pectobacterium carotovorum]
ATGCCGAATATTATATTGAGTGATACCAGTGCCAGCGTCAGTGAATTGAAAAAGAACCCGATGGCGACGGTCAATGCTGG
CGACGGTCTACCTGTCGCTATTTTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTTTACGAAAAAATGC
TGGATGCGCTGGACGACCAGGAACTGGTTAAGCTAATCGGTGAACGCAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8Q6Q4

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References