Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 2611201..2611736 | Replicon | chromosome |
Accession | NZ_CP032619 | ||
Organism | Pectobacterium carotovorum strain HG-49 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A7V8Q6Q4 |
Locus tag | D7Z95_RS11755 | Protein ID | WP_039284929.1 |
Coordinates | 2611201..2611488 (-) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q6DB37 |
Locus tag | D7Z95_RS11760 | Protein ID | WP_010281712.1 |
Coordinates | 2611485..2611736 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D7Z95_RS11740 | 2607688..2608416 | - | 729 | WP_043881851.1 | DUF1266 domain-containing protein | - |
D7Z95_RS11745 | 2608770..2609612 | + | 843 | WP_015842271.1 | 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ | - |
D7Z95_RS11750 | 2609741..2611093 | + | 1353 | WP_181848045.1 | glutathione-disulfide reductase | - |
D7Z95_RS11755 | 2611201..2611488 | - | 288 | WP_039284929.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
D7Z95_RS11760 | 2611485..2611736 | - | 252 | WP_010281712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
D7Z95_RS11765 | 2611991..2612896 | + | 906 | WP_205947289.1 | siderophore-interacting protein | - |
D7Z95_RS11770 | 2612931..2613686 | - | 756 | WP_205947288.1 | thiol:disulfide interchange protein DsbG | - |
D7Z95_RS11775 | 2613756..2614460 | - | 705 | WP_205947287.1 | SMI1/KNR4 family protein | - |
D7Z95_RS11780 | 2614642..2615265 | + | 624 | WP_194431385.1 | LysE family translocator | - |
D7Z95_RS11785 | 2615308..2616441 | - | 1134 | WP_205947286.1 | alkylhydroperoxidase domain protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11088.18 Da Isoelectric Point: 10.3527
>T112012 WP_039284929.1 NZ_CP032619:c2611488-2611201 [Pectobacterium carotovorum]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDILIIAVVAVGK
RERSGVYHLASERMR
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDILIIAVVAVGK
RERSGVYHLASERMR
Download Length: 288 bp
>T112012 NZ_CP032619:c2611488-2611201 [Pectobacterium carotovorum]
ATGAGCTATAGCGTCAAATTCAGGGAAGATGCGCTGAAAGAATGGCTCAAGCTCGATAAAACCATCCAACAGCAATTTGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCTCATATTCCTTCGGCAAAGTTACGGGGGATGAAGGACTGCTACAAAATAA
AGCTCCGAGCATCAGGCTTTCGTTTGGTTTATGAAGTCATTGACGACATCTTGATTATTGCCGTGGTGGCGGTAGGTAAA
CGTGAACGCAGCGGTGTTTATCATCTGGCGAGTGAGCGAATGAGATAA
ATGAGCTATAGCGTCAAATTCAGGGAAGATGCGCTGAAAGAATGGCTCAAGCTCGATAAAACCATCCAACAGCAATTTGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCTCATATTCCTTCGGCAAAGTTACGGGGGATGAAGGACTGCTACAAAATAA
AGCTCCGAGCATCAGGCTTTCGTTTGGTTTATGAAGTCATTGACGACATCTTGATTATTGCCGTGGTGGCGGTAGGTAAA
CGTGAACGCAGCGGTGTTTATCATCTGGCGAGTGAGCGAATGAGATAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9117.47 Da Isoelectric Point: 4.0637
>AT112012 WP_010281712.1 NZ_CP032619:c2611736-2611485 [Pectobacterium carotovorum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL
Download Length: 252 bp
>AT112012 NZ_CP032619:c2611736-2611485 [Pectobacterium carotovorum]
ATGCCGAATATTATATTGAGTGATACCAGTGCCAGCGTCAGTGAATTGAAAAAGAACCCGATGGCGACGGTCAATGCTGG
CGACGGTCTACCTGTCGCTATTTTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTTTACGAAAAAATGC
TGGATGCGCTGGACGACCAGGAACTGGTTAAGCTAATCGGTGAACGCAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA
ATGCCGAATATTATATTGAGTGATACCAGTGCCAGCGTCAGTGAATTGAAAAAGAACCCGATGGCGACGGTCAATGCTGG
CGACGGTCTACCTGTCGCTATTTTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTTTACGAAAAAATGC
TGGATGCGCTGGACGACCAGGAACTGGTTAAGCTAATCGGTGAACGCAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8Q6Q4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0M2EZP0 |