Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2877683..2878929 Replicon chromosome
Accession NZ_CP032618
Organism Pseudomonas fluorescens strain PF08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D7M10_RS13320 Protein ID WP_057438408.1
Coordinates 2878348..2878929 (+) Length 194 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D7M10_RS13315 Protein ID WP_057959728.1
Coordinates 2877683..2878240 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7M10_RS13290 2872899..2873294 - 396 WP_120732970.1 hypothetical protein -
D7M10_RS13295 2873687..2874076 + 390 WP_120732971.1 MerR family transcriptional regulator -
D7M10_RS13300 2874042..2875022 - 981 WP_169990097.1 NAD-dependent epimerase/dehydratase family protein -
D7M10_RS13305 2875195..2875734 + 540 WP_057959730.1 adenylate kinase -
D7M10_RS13310 2875912..2877525 + 1614 WP_057959729.1 methyl-accepting chemotaxis protein -
D7M10_RS13315 2877683..2878240 + 558 WP_057959728.1 helix-turn-helix domain-containing protein Antitoxin
D7M10_RS13320 2878348..2878929 + 582 WP_057438408.1 HD domain-containing protein Toxin
D7M10_RS13325 2878926..2879138 - 213 Protein_2571 helix-turn-helix domain-containing protein -
D7M10_RS13330 2879577..2880431 + 855 WP_057959726.1 DMT family transporter -
D7M10_RS13335 2880694..2881179 + 486 WP_120732975.1 ATP-binding protein -
D7M10_RS13340 2881503..2881958 + 456 WP_057438411.1 hypothetical protein -
D7M10_RS13345 2882069..2883291 + 1223 WP_162947727.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-154)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 194 a.a.        Molecular weight: 21835.78 Da        Isoelectric Point: 4.7666

>T112006 WP_057438408.1 NZ_CP032618:2878348-2878929 [Pseudomonas fluorescens]
MDIEKIKGRLEFLREAEKLKDVLRSAHTSCGRTESTAEHSWRLCLMAIVFGDYLTDLDRLKMLKMCVIHDLGEAINGDVP
AINQDAFPNKSEQERNDLLLLTSALDEPLKAEILALWDDYENASSPEAVAVKALDKLETMLQHNQGKNPTGFDYEFNLAY
GKKYTDAAPLFEALRTIIDQDTKEHILANSKNH

Download         Length: 582 bp

>T112006 NZ_CP032618:2878348-2878929 [Pseudomonas fluorescens]
ATGGACATCGAAAAAATCAAAGGGCGCCTCGAATTTCTACGCGAGGCGGAAAAACTCAAGGACGTGCTTAGAAGCGCGCA
CACCTCTTGCGGGCGCACCGAAAGCACGGCGGAGCATAGCTGGCGCCTTTGCCTGATGGCCATTGTCTTTGGGGACTACC
TGACTGATCTCGATCGGCTGAAAATGCTCAAGATGTGTGTTATCCACGACTTGGGGGAGGCCATTAACGGAGATGTTCCC
GCCATTAATCAAGATGCGTTTCCCAACAAGAGCGAGCAAGAGAGAAACGATCTCCTGCTCTTGACCAGTGCCCTGGATGA
ACCGTTAAAGGCCGAGATACTGGCGCTTTGGGATGACTATGAAAATGCTTCGTCGCCAGAGGCCGTAGCCGTCAAGGCGC
TGGATAAGTTGGAGACGATGCTGCAGCACAACCAAGGCAAGAACCCAACGGGCTTCGATTACGAATTCAATCTTGCCTAT
GGCAAAAAATACACAGATGCGGCGCCGCTGTTTGAGGCGCTGCGCACTATCATCGACCAGGACACCAAAGAACACATACT
GGCGAATTCTAAAAATCACTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20669.08 Da        Isoelectric Point: 9.5912

>AT112006 WP_057959728.1 NZ_CP032618:2877683-2878240 [Pseudomonas fluorescens]
MSDMLLSPVLPGVMLRRWRLLHRVKQSHAAELFNVTQSTISRWESGVLELDPLAHKKLEQLLAARLTTAADKALGRMVRE
SSRPVHLMCDLTHRLLACSPSRAAQFTSPVSELLGRSLWRFATPNIISTELALDKLGWREAFAPPALEFLTGDNNSSIVP
ISQSLCRWTRMPLCDGTTARLVESL

Download         Length: 558 bp

>AT112006 NZ_CP032618:2877683-2878240 [Pseudomonas fluorescens]
ATGTCTGACATGTTGCTAAGTCCTGTCTTACCCGGCGTTATGCTCAGGCGATGGCGCCTGTTACACCGGGTCAAACAATC
CCATGCCGCGGAGCTGTTTAACGTCACTCAATCGACTATCTCTCGCTGGGAGAGTGGCGTACTCGAGTTGGATCCTCTCG
CGCACAAAAAGCTTGAGCAATTGCTGGCCGCTCGTCTCACCACCGCGGCGGATAAAGCGCTGGGACGAATGGTGCGGGAA
AGCTCGCGTCCTGTTCATCTCATGTGTGATTTGACGCACCGTCTACTTGCTTGTTCTCCTTCGCGCGCCGCCCAGTTCAC
GAGTCCGGTCAGTGAACTGCTGGGTCGCTCGCTATGGCGCTTCGCTACGCCCAATATCATCAGCACCGAGCTCGCCCTGG
ATAAATTGGGTTGGCGGGAAGCCTTTGCACCCCCCGCGCTGGAGTTTCTGACGGGTGACAATAATTCGTCCATCGTTCCG
ATTAGCCAAAGCCTGTGTCGTTGGACGCGTATGCCCCTGTGCGACGGAACAACAGCGCGCTTGGTCGAGTCGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References