Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 2830096..2831510 Replicon chromosome
Accession NZ_CP032616
Organism Pseudomonas sp. DY-1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag D6Z43_RS13375 Protein ID WP_120652671.1
Coordinates 2830941..2831510 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag D6Z43_RS13370 Protein ID WP_120652670.1
Coordinates 2830096..2830938 (-) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D6Z43_RS13345 2825468..2826412 + 945 WP_120652665.1 bile acid:sodium symporter family protein -
D6Z43_RS13350 2826554..2826868 + 315 WP_120652666.1 quaternary ammonium compound efflux SMR transporter SugE -
D6Z43_RS13355 2826911..2828785 - 1875 WP_120652667.1 MFS transporter -
D6Z43_RS13360 2829017..2829346 - 330 WP_120652668.1 AzlD domain-containing protein -
D6Z43_RS13365 2829328..2830059 - 732 WP_120652669.1 AzlC family ABC transporter permease -
D6Z43_RS13370 2830096..2830938 - 843 WP_120652670.1 AraC family transcriptional regulator Antitoxin
D6Z43_RS13375 2830941..2831510 - 570 WP_120652671.1 GNAT family N-acetyltransferase Toxin
D6Z43_RS13380 2831762..2835241 + 3480 WP_120652672.1 hybrid sensor histidine kinase/response regulator -
D6Z43_RS13385 2835295..2835714 - 420 WP_120655258.1 hypothetical protein -
D6Z43_RS13390 2835883..2836473 + 591 WP_120652673.1 Crp/Fnr family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(19-150)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21221.24 Da        Isoelectric Point: 8.5369

>T111997 WP_120652671.1 NZ_CP032616:c2831510-2830941 [Pseudomonas sp. DY-1]
MFNPQPVILQRGALRLEPLAEADIPALVTLAEANREALAYMNGPLRPDWYRHALADQREGRAVVFAIRLGDNLVGTTRFS
DFMPNLPAAEIGWTWLAAGEHGSGLNASIKYLMLRHAFEEWQVVRVQLKTAASNLRSQRAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDHDWPGVKQRLEALFSA

Download         Length: 570 bp

>T111997 NZ_CP032616:c2831510-2830941 [Pseudomonas sp. DY-1]
ATGTTCAATCCACAACCGGTCATCCTGCAGCGCGGCGCCTTGCGCCTCGAACCGCTGGCAGAGGCCGACATCCCGGCGCT
GGTTACCCTGGCTGAGGCCAACCGCGAAGCCCTGGCCTACATGAACGGCCCCCTGCGACCCGACTGGTATCGCCACGCCC
TGGCCGACCAGCGGGAAGGGCGGGCGGTGGTCTTCGCCATTCGCCTGGGTGACAACCTGGTAGGCACCACGCGTTTCTCC
GATTTCATGCCCAACCTGCCGGCCGCCGAGATTGGCTGGACCTGGCTCGCCGCCGGTGAGCACGGCAGTGGCCTGAATGC
CTCGATCAAGTATCTGATGCTGCGCCATGCATTCGAGGAGTGGCAAGTGGTGCGGGTGCAACTGAAAACCGCCGCCAGCA
ACCTGCGCTCCCAGCGCGCCATCGAAAAGCTCGGCGCCCAGCGCGAGGGCGTGCTGCGCAACCATCGTCGCCTGGCTGAC
GGCCGCCTTGACGACAGCGTGCTATACAGCATCACCGACCACGACTGGCCGGGAGTGAAGCAACGGCTGGAGGCGCTGTT
CAGCGCATAA

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31281.54 Da        Isoelectric Point: 8.0924

>AT111997 WP_120652670.1 NZ_CP032616:c2830938-2830096 [Pseudomonas sp. DY-1]
MGEHREDAHFWQAGHLDGLELLSARYIEHRFAPHVHDGYVIAVVEAGAERYRYRGVDHLAGAGSLALINPDEVHTGSKGH
DDGWRYRVFYPDIALVRSALEELELPLAGMPAFIGSVHHDPDLVQMFTHLHRLLEANASALQQQTAWREALLSLFRRHSR
LPEPGAPGREPLAVLRAKELLRERLAEPPSLEELATAVKLSPFHFARTFRRATGMPPHAWLKQQRLDQARALLKAGCAPA
GVAAQLGFADQSHLTRQFKQAYGVGPGEYRNACARSFKTH

Download         Length: 843 bp

>AT111997 NZ_CP032616:c2830938-2830096 [Pseudomonas sp. DY-1]
TTGGGCGAGCATAGGGAAGACGCGCATTTCTGGCAGGCGGGCCATCTGGATGGCCTGGAGCTGCTGTCTGCTCGCTACAT
CGAACATCGCTTCGCCCCCCATGTACACGACGGCTATGTGATCGCCGTGGTGGAGGCAGGGGCCGAGCGCTATCGCTATC
GCGGCGTCGATCACCTGGCCGGTGCCGGCAGCCTGGCGCTGATCAACCCGGATGAGGTGCACACCGGTTCCAAGGGACAC
GACGACGGTTGGCGCTACCGGGTGTTCTATCCGGATATCGCGTTGGTACGCAGCGCCCTGGAGGAGCTCGAGCTTCCTCT
GGCTGGCATGCCGGCCTTTATCGGCAGCGTTCATCACGATCCCGACCTGGTCCAGATGTTCACCCATCTGCATCGGCTGC
TGGAGGCAAATGCCAGTGCCCTGCAACAGCAGACTGCCTGGCGCGAGGCCCTGTTGTCGCTGTTCCGTCGTCATTCCAGG
CTGCCCGAGCCCGGCGCCCCGGGCCGTGAGCCTCTGGCTGTGCTGCGTGCCAAGGAACTGCTGCGTGAACGCCTGGCCGA
GCCGCCGTCCCTCGAGGAACTGGCCACTGCCGTGAAGCTCTCGCCATTCCATTTCGCTCGTACCTTCCGCCGCGCCACCG
GCATGCCGCCCCACGCCTGGCTCAAGCAGCAGCGCCTGGATCAGGCCCGTGCCCTGCTCAAGGCCGGTTGCGCGCCAGCC
GGTGTGGCGGCACAGCTGGGGTTCGCCGATCAGAGCCATCTGACCCGCCAGTTCAAGCAGGCTTATGGCGTGGGGCCGGG
CGAATATCGCAACGCGTGCGCAAGATCGTTCAAGACGCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References