Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PhRel2-ATphRel2/DUF4065(antitoxin) |
Location | 1812029..1813491 | Replicon | chromosome |
Accession | NZ_CP032538 | ||
Organism | Bacillus licheniformis strain MT-B06 |
Toxin (Protein)
Gene name | phRel2 | Uniprot ID | - |
Locus tag | D6022_RS09475 | Protein ID | WP_017474550.1 |
Coordinates | 1812029..1812739 (+) | Length | 237 a.a. |
Antitoxin (Protein)
Gene name | ATphRel2 | Uniprot ID | - |
Locus tag | D6022_RS09480 | Protein ID | WP_017474549.1 |
Coordinates | 1812742..1813491 (+) | Length | 250 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D6022_RS09430 | 1807125..1807307 | + | 183 | WP_017474916.1 | XkdX family protein | - |
D6022_RS09435 | 1807408..1808241 | + | 834 | WP_017474917.1 | hypothetical protein | - |
D6022_RS09440 | 1808324..1808593 | + | 270 | WP_017474918.1 | hemolysin XhlA family protein | - |
D6022_RS09445 | 1808609..1808872 | + | 264 | WP_017474919.1 | phage holin | - |
D6022_RS09450 | 1808924..1810003 | + | 1080 | WP_075218312.1 | N-acetylmuramoyl-L-alanine amidase | - |
D6022_RS23885 | 1810011..1810157 | + | 147 | WP_017474554.1 | hypothetical protein | - |
D6022_RS09455 | 1810423..1810596 | - | 174 | WP_017474553.1 | hypothetical protein | - |
D6022_RS09460 | 1810644..1811453 | - | 810 | WP_017474552.1 | ATP-dependent DNA ligase | - |
D6022_RS09465 | 1811579..1811668 | + | 90 | Protein_1824 | peptidoglycan-binding protein | - |
D6022_RS09470 | 1811674..1811757 | + | 84 | Protein_1825 | LysM peptidoglycan-binding domain-containing protein | - |
D6022_RS09475 | 1812029..1812739 | + | 711 | WP_017474550.1 | hypothetical protein | Toxin |
D6022_RS09480 | 1812742..1813491 | + | 750 | WP_017474549.1 | DUF4065 domain-containing protein | Antitoxin |
D6022_RS09490 | 1813850..1815031 | - | 1182 | WP_016886467.1 | oxalate decarboxylase family bicupin | - |
D6022_RS09495 | 1815346..1816527 | + | 1182 | WP_003184708.1 | alanine racemase | - |
D6022_RS09500 | 1816702..1817619 | + | 918 | WP_003184707.1 | class I SAM-dependent methyltransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1760914..1813491 | 52577 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 237 a.a. Molecular weight: 28189.80 Da Isoelectric Point: 6.8925
>T111957 WP_017474550.1 NZ_CP032538:1812029-1812739 [Bacillus licheniformis]
VINCTCEVESFCYSFYNLIVEINEAHSEFSKEFASEKQDALINLKRKQVNHVTQVKNGNTFSVDNLFLQLISNYREKLLD
YIATDVDFESQYTDLILRARTKESTSIINKLKYYLVGKNEAGKLPLNKCLNDLFGFRIHPTFFDHNKECFQETCQRLKQL
YKNRIDFRDSSKGNYKAYHIYLYGESWEYFPWEIQVWRLSDREQNDLSHKQHKQEHRKWAAIYKNSTEIELEMEGV
VINCTCEVESFCYSFYNLIVEINEAHSEFSKEFASEKQDALINLKRKQVNHVTQVKNGNTFSVDNLFLQLISNYREKLLD
YIATDVDFESQYTDLILRARTKESTSIINKLKYYLVGKNEAGKLPLNKCLNDLFGFRIHPTFFDHNKECFQETCQRLKQL
YKNRIDFRDSSKGNYKAYHIYLYGESWEYFPWEIQVWRLSDREQNDLSHKQHKQEHRKWAAIYKNSTEIELEMEGV
Download Length: 711 bp
>T111957 NZ_CP032538:1812029-1812739 [Bacillus licheniformis]
GTGATTAATTGTACGTGTGAAGTAGAGTCATTTTGTTATAGTTTTTATAACTTAATAGTTGAAATTAATGAAGCGCATAG
TGAATTTTCAAAAGAGTTCGCTTCTGAAAAACAAGATGCTCTAATTAACTTAAAAAGAAAACAAGTTAATCATGTTACTC
AAGTAAAAAATGGGAACACTTTTTCTGTTGATAATTTGTTTTTGCAGTTGATTTCAAATTATCGAGAGAAGTTGCTTGAT
TATATTGCAACTGATGTTGATTTTGAAAGTCAATATACGGATTTAATTCTAAGGGCAAGAACTAAGGAATCCACTTCAAT
CATTAATAAGCTTAAATATTATCTTGTTGGAAAAAATGAAGCAGGAAAACTACCTCTTAACAAATGCTTGAATGATTTAT
TTGGATTTAGAATACATCCAACATTTTTTGACCATAATAAGGAATGTTTTCAAGAGACATGTCAAAGGTTAAAGCAACTA
TATAAAAATCGAATTGATTTTAGGGATTCATCAAAGGGAAATTATAAAGCGTATCATATTTATTTATACGGAGAGAGTTG
GGAATACTTCCCTTGGGAAATACAAGTATGGCGCTTAAGTGATCGTGAACAGAATGATTTATCGCATAAGCAGCATAAAC
AAGAACATAGGAAATGGGCTGCAATTTACAAAAATTCAACAGAAATAGAATTAGAAATGGAAGGTGTTTAG
GTGATTAATTGTACGTGTGAAGTAGAGTCATTTTGTTATAGTTTTTATAACTTAATAGTTGAAATTAATGAAGCGCATAG
TGAATTTTCAAAAGAGTTCGCTTCTGAAAAACAAGATGCTCTAATTAACTTAAAAAGAAAACAAGTTAATCATGTTACTC
AAGTAAAAAATGGGAACACTTTTTCTGTTGATAATTTGTTTTTGCAGTTGATTTCAAATTATCGAGAGAAGTTGCTTGAT
TATATTGCAACTGATGTTGATTTTGAAAGTCAATATACGGATTTAATTCTAAGGGCAAGAACTAAGGAATCCACTTCAAT
CATTAATAAGCTTAAATATTATCTTGTTGGAAAAAATGAAGCAGGAAAACTACCTCTTAACAAATGCTTGAATGATTTAT
TTGGATTTAGAATACATCCAACATTTTTTGACCATAATAAGGAATGTTTTCAAGAGACATGTCAAAGGTTAAAGCAACTA
TATAAAAATCGAATTGATTTTAGGGATTCATCAAAGGGAAATTATAAAGCGTATCATATTTATTTATACGGAGAGAGTTG
GGAATACTTCCCTTGGGAAATACAAGTATGGCGCTTAAGTGATCGTGAACAGAATGATTTATCGCATAAGCAGCATAAAC
AAGAACATAGGAAATGGGCTGCAATTTACAAAAATTCAACAGAAATAGAATTAGAAATGGAAGGTGTTTAG
Antitoxin
Download Length: 250 a.a. Molecular weight: 29056.07 Da Isoelectric Point: 6.4106
>AT111957 WP_017474549.1 NZ_CP032538:1812742-1813491 [Bacillus licheniformis]
MAFHFIAIVSDFSGGRRYGWHYSSEDRLDKDYIKSFMTKVKQKCGHIQFGIHKLTTEDTSWASVVRMDSFFDDVIITNRI
DDFIDVVANDQQLSAYDVAKFVLATLPTSHLKLQKLLYYIYSEFLVRTGEKLFKDRIVAYKYGPVVEDVFHKYRKHGSSE
IDYKEDATFVLRTDEQAFTPSLMKIWTSEYGVAALECIIETLEKYGDLDAFRLVDKTHQKGGPWERVYKPGQNCEITDEL
ITLYHKYVQ
MAFHFIAIVSDFSGGRRYGWHYSSEDRLDKDYIKSFMTKVKQKCGHIQFGIHKLTTEDTSWASVVRMDSFFDDVIITNRI
DDFIDVVANDQQLSAYDVAKFVLATLPTSHLKLQKLLYYIYSEFLVRTGEKLFKDRIVAYKYGPVVEDVFHKYRKHGSSE
IDYKEDATFVLRTDEQAFTPSLMKIWTSEYGVAALECIIETLEKYGDLDAFRLVDKTHQKGGPWERVYKPGQNCEITDEL
ITLYHKYVQ
Download Length: 750 bp
>AT111957 NZ_CP032538:1812742-1813491 [Bacillus licheniformis]
ATGGCTTTTCATTTTATTGCAATCGTAAGTGACTTCTCTGGTGGGAGAAGATACGGTTGGCATTATTCAAGTGAAGACAG
GTTAGATAAAGATTATATTAAGTCTTTTATGACCAAAGTTAAACAAAAATGTGGACATATTCAATTTGGAATTCATAAAC
TAACTACTGAGGATACATCTTGGGCTTCAGTAGTAAGAATGGATTCGTTCTTTGATGATGTTATAATAACAAATCGAATT
GACGACTTTATAGATGTTGTTGCAAATGATCAACAGCTTTCCGCTTATGATGTTGCTAAATTCGTACTAGCTACGCTCCC
TACATCACATTTGAAATTGCAAAAGTTGCTATACTATATCTACTCTGAATTTCTGGTCAGAACTGGGGAAAAATTATTCA
AAGATCGGATAGTTGCTTATAAGTATGGACCTGTAGTAGAAGATGTTTTTCATAAGTATCGAAAACATGGTAGCTCGGAA
ATTGATTATAAAGAGGATGCGACTTTCGTGTTGCGAACAGATGAACAAGCATTTACACCCTCTTTAATGAAAATTTGGAC
TTCTGAATATGGAGTAGCAGCGTTAGAATGTATTATAGAAACATTGGAGAAATATGGTGATCTAGATGCATTCAGGTTAG
TTGACAAAACTCATCAAAAAGGGGGGCCATGGGAAAGAGTTTATAAACCTGGTCAAAATTGTGAAATCACTGATGAGTTA
ATAACTCTATATCATAAATATGTACAATAA
ATGGCTTTTCATTTTATTGCAATCGTAAGTGACTTCTCTGGTGGGAGAAGATACGGTTGGCATTATTCAAGTGAAGACAG
GTTAGATAAAGATTATATTAAGTCTTTTATGACCAAAGTTAAACAAAAATGTGGACATATTCAATTTGGAATTCATAAAC
TAACTACTGAGGATACATCTTGGGCTTCAGTAGTAAGAATGGATTCGTTCTTTGATGATGTTATAATAACAAATCGAATT
GACGACTTTATAGATGTTGTTGCAAATGATCAACAGCTTTCCGCTTATGATGTTGCTAAATTCGTACTAGCTACGCTCCC
TACATCACATTTGAAATTGCAAAAGTTGCTATACTATATCTACTCTGAATTTCTGGTCAGAACTGGGGAAAAATTATTCA
AAGATCGGATAGTTGCTTATAAGTATGGACCTGTAGTAGAAGATGTTTTTCATAAGTATCGAAAACATGGTAGCTCGGAA
ATTGATTATAAAGAGGATGCGACTTTCGTGTTGCGAACAGATGAACAAGCATTTACACCCTCTTTAATGAAAATTTGGAC
TTCTGAATATGGAGTAGCAGCGTTAGAATGTATTATAGAAACATTGGAGAAATATGGTGATCTAGATGCATTCAGGTTAG
TTGACAAAACTCATCAAAAAGGGGGGCCATGGGAAAGAGTTTATAAACCTGGTCAAAATTGTGAAATCACTGATGAGTTA
ATAACTCTATATCATAAATATGTACAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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