111935

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PsyrTA/-
Location 1110117..1111456 Replicon chromosome
Accession NZ_CP032523
Organism Shigella sonnei strain AR_0030

Toxin (Protein)


Gene name PsyrT Uniprot ID -
Locus tag AM357_RS05910 Protein ID WP_001119379.1
Coordinates 1111319..1111456 (-) Length 46 a.a.

Antitoxin (Protein)


Gene name PsyrA Uniprot ID -
Locus tag AM357_RS05905 Protein ID WP_001053685.1
Coordinates 1110117..1111319 (-) Length 401 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM357_RS05890 (1105724) 1105724..1107910 - 2187 WP_001283723.1 1,4-alpha-glucan branching enzyme -
AM357_RS27255 (1108068) 1108068..1108109 - 42 Protein_1137 hypothetical protein -
AM357_RS05895 (1108183) 1108183..1109286 - 1104 WP_000799956.1 aspartate-semialdehyde dehydrogenase -
AM357_RS05900 (1109478) 1109478..1110071 + 594 WP_001002544.1 NAAT family transporter YhgN -
AM357_RS05905 (1110117) 1110117..1111319 - 1203 WP_001053685.1 DNA-processing protein DprA Antitoxin
AM357_RS05910 (1111319) 1111319..1111456 - 138 WP_001119379.1 hypothetical protein Toxin
AM357_RS05920 (1112255) 1112255..1114066 - 1812 WP_005140413.1 helicase-related protein -
AM357_RS05925 (1114207) 1114207..1115547 - 1341 WP_000210100.1 gluconate transporter -
AM357_RS05930 (1115551) 1115551..1116078 - 528 WP_000108330.1 gluconokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Phosphoribosyltransferase domain

(6-34)

Antitoxin

DNA recombination-mediator protein A

(86-398)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 4683.50 Da        Isoelectric Point: 4.3115

>T111935 WP_001119379.1 NZ_CP032523:c1111456-1111319 [Shigella sonnei]
MPGPALLVDDIVDSAWTLTVLTALLRQAGCPTVYPLALASTSVKN

Download         Length: 138 bp

>T111935 NZ_CP032523:c1111456-1111319 [Shigella sonnei]
ATGCCTGGTCCGGCGTTGCTGGTTGACGATATCGTGGATTCTGCATGGACGCTGACAGTTCTGACAGCACTGTTACGCCA
GGCAGGTTGCCCGACGGTTTATCCTCTTGCCCTTGCTTCTACCTCGGTAAAAAATTGA

Antitoxin


Download         Length: 401 a.a.        Molecular weight: 43840.26 Da        Isoelectric Point: 6.6429

>AT111935 WP_001053685.1 NZ_CP032523:c1111319-1110117 [Shigella sonnei]
MNLSANAQATLLLTSDFSRAAASEYKPLSNSEWGKFALWLKHQRISPAELLVPQPQEKLTGWSDPRISQERILGLLARGH
SLVLAVDKWQRAGLWILTRGDADYPVRLKNRLRTDAPPVLFGCGNKALLQAEGMAIVGSRDAPTDDLRYTQQLAAKLAQQ
GICVISGGARGIDECAMASALEAGGTAVGVLADSLLKTSTLVKWREGLIAGNLVLISPFYPEVRFTVGNAMARNKYIYCL
AESAMVVRAGMTGGTITGAMEALKHQWLPVQVKPNQDMQSANSRLVENGASWSAEQAENVTIRLPDVPGLMYDRALRNAQ
PELFSLHEDDANYAVMPAYTPVDFYQLFVAELAILAKESISIERLASCTGLTIEQISVWLNRAEEEGRVIRLGEGHYQFR

Download         Length: 1203 bp

>AT111935 NZ_CP032523:c1111319-1110117 [Shigella sonnei]
ATGAATCTTTCAGCCAATGCACAAGCAACTCTCCTGCTAACCAGCGATTTTTCTCGCGCGGCGGCGAGTGAGTATAAACC
TCTTAGTAATAGTGAATGGGGGAAGTTTGCATTATGGCTGAAGCACCAACGTATCAGTCCCGCCGAGCTTCTGGTGCCGC
AACCGCAAGAGAAACTTACAGGCTGGAGCGATCCGCGTATTTCTCAGGAGCGTATTCTTGGCTTGCTGGCGCGTGGTCAT
AGTCTGGTGTTGGCGGTAGATAAGTGGCAACGCGCCGGTTTATGGATCTTAACCCGCGGAGATGCTGATTATCCCGTTCG
CTTGAAAAACCGATTGCGAACGGATGCACCTCCCGTTTTATTTGGCTGCGGGAATAAAGCATTACTGCAAGCGGAAGGTA
TGGCGATTGTTGGCTCGCGAGATGCTCCGACTGACGATTTGCGCTATACCCAACAACTGGCCGCGAAACTGGCCCAACAG
GGGATTTGCGTTATCTCTGGTGGTGCGCGAGGTATTGATGAATGTGCAATGGCGTCGGCACTGGAGGCCGGGGGAACTGC
CGTTGGCGTATTAGCTGATAGCTTGTTAAAAACGAGTACGTTAGTGAAATGGCGTGAAGGGCTTATAGCAGGCAACCTGG
TGTTGATTTCGCCGTTTTACCCAGAGGTACGTTTCACCGTCGGCAATGCGATGGCGCGAAATAAATATATTTATTGCCTT
GCTGAAAGCGCAATGGTTGTACGTGCGGGAATGACCGGTGGAACGATAACCGGGGCGATGGAGGCATTAAAACATCAGTG
GCTGCCTGTGCAGGTTAAACCAAATCAGGATATGCAATCAGCCAATTCACGATTAGTAGAAAATGGGGCGTCATGGAGTG
CTGAACAGGCTGAGAATGTGACGATCAGACTGCCAGACGTTCCTGGGCTGATGTATGACAGAGCACTCCGTAACGCTCAA
CCAGAACTGTTTTCGCTGCATGAAGATGACGCAAATTACGCAGTAATGCCCGCGTATACGCCTGTCGATTTTTATCAACT
CTTTGTGGCGGAACTGGCGATCCTTGCAAAGGAATCGATAAGTATTGAAAGGCTGGCGTCTTGTACTGGTTTAACCATCG
AACAAATTAGTGTGTGGCTGAACCGCGCAGAAGAAGAGGGAAGGGTTATCCGATTGGGCGAAGGTCATTATCAGTTCAGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References