Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 3839214..3839809 Replicon chromosome
Accession NZ_CP032521
Organism Alcaligenes faecalis strain J481

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D6I95_RS17690 Protein ID WP_123051553.1
Coordinates 3839504..3839809 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D6I95_RS17685 Protein ID WP_123051552.1
Coordinates 3839214..3839507 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D6I95_RS17665 3834512..3835903 + 1392 WP_123051549.1 dNTP triphosphohydrolase -
D6I95_RS18030 3836709..3836915 + 207 WP_164461445.1 hypothetical protein -
D6I95_RS17670 3836908..3837201 + 294 WP_164461446.1 antitoxin VbhA family protein -
D6I95_RS17680 3837983..3838915 + 933 WP_205649106.1 hypothetical protein -
D6I95_RS17685 3839214..3839507 - 294 WP_123051552.1 putative addiction module antidote protein Antitoxin
D6I95_RS17690 3839504..3839809 - 306 WP_123051553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D6I95_RS17695 3840196..3840900 - 705 WP_123051554.1 SDR family oxidoreductase -
D6I95_RS17700 3841004..3841900 + 897 WP_123051555.1 LysR family transcriptional regulator -
D6I95_RS17705 3842069..3842773 - 705 WP_123051556.1 helix-turn-helix domain-containing protein -
D6I95_RS17710 3842932..3844365 + 1434 WP_164461447.1 amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3825981..3839809 13828


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-88)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11485.21 Da        Isoelectric Point: 10.2587

>T111930 WP_123051553.1 NZ_CP032521:c3839809-3839504 [Alcaligenes faecalis]
MNTINRSETFSTWLTGLKDLKARAKIVVRIKQASLGNFGDVKPISDGVYEMRIHFGPGYRLYYAREGRVVYLLLSGGDKS
SQKQDIKTAIAMWKQIQEDQS

Download         Length: 306 bp

>T111930 NZ_CP032521:c3839809-3839504 [Alcaligenes faecalis]
ATGAACACGATCAACCGCAGCGAAACCTTCAGCACCTGGCTGACAGGCTTAAAAGACCTCAAAGCCAGAGCGAAGATCGT
GGTTCGCATCAAACAAGCCAGCTTGGGCAATTTCGGAGACGTAAAGCCAATTAGTGATGGTGTGTATGAAATGCGCATCC
ACTTCGGTCCCGGCTACCGTCTCTACTATGCTCGTGAGGGCCGTGTGGTCTATCTGCTGCTTAGCGGTGGCGACAAGTCC
TCCCAAAAACAAGACATCAAAACTGCAATCGCCATGTGGAAACAAATTCAGGAGGATCAGTCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10337.89 Da        Isoelectric Point: 4.8359

>AT111930 WP_123051552.1 NZ_CP032521:c3839507-3839214 [Alcaligenes faecalis]
MTTLKTAPFDAAEYLDNEEAIAEYLSAALEEDDPALFLSALADVVKARGMTKMAKDAGVGRESLYKALAPGAKPRYDTVL
KLARAAGVKLTVEPIHA

Download         Length: 294 bp

>AT111930 NZ_CP032521:c3839507-3839214 [Alcaligenes faecalis]
ATGACCACCCTCAAAACAGCCCCCTTCGACGCCGCCGAATATCTTGATAACGAGGAAGCTATTGCCGAGTACCTCTCGGC
TGCTTTGGAAGAAGACGATCCAGCCTTGTTCCTCTCTGCTCTTGCGGATGTGGTCAAAGCCCGAGGCATGACAAAAATGG
CTAAAGACGCCGGTGTAGGCCGAGAAAGCCTGTACAAGGCTCTTGCTCCGGGCGCCAAGCCACGATATGACACTGTCCTG
AAGTTAGCGCGGGCTGCTGGGGTGAAATTAACGGTAGAACCGATTCATGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References