Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1245228..1245462 | Replicon | chromosome |
| Accession | NZ_CP032513 | ||
| Organism | Shigella flexneri strain SFL1520 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1245358..1245461 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1245228..1245462 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D6T62_RS06610 | 1241783..1242445 | - | 663 | WP_000944269.1 | exodeoxyribonuclease X | - |
| D6T62_RS06615 | 1242469..1243125 | - | 657 | WP_000011667.1 | carbon-nitrogen hydrolase family protein YobB | - |
| D6T62_RS06620 | 1243227..1243457 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| D6T62_RS06625 | 1243596..1243970 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| D6T62_RS06630 | 1243974..1244846 | + | 873 | Protein_1266 | copper homeostasis membrane protein CopD | - |
| D6T62_RS06635 | 1244859..1245200 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1245228..1245462 | - | 235 | - | - | Antitoxin |
| - | 1245358..1245461 | + | 104 | - | - | Toxin |
| D6T62_RS06640 | 1245593..1246670 | - | 1078 | Protein_1268 | phage integrase Arm DNA-binding domain-containing protein | - |
| D6T62_RS06645 | 1246636..1246917 | - | 282 | WP_005127484.1 | excisionase | - |
| D6T62_RS06655 | 1248291..1248479 | - | 189 | WP_000276807.1 | DUF1187 family protein | - |
| - | 1248295..1248473 | + | 179 | NuclAT_0 | - | - |
| - | 1248295..1248473 | + | 179 | NuclAT_0 | - | - |
| - | 1248295..1248473 | + | 179 | NuclAT_0 | - | - |
| - | 1248295..1248473 | + | 179 | NuclAT_0 | - | - |
| D6T62_RS06660 | 1248530..1249627 | - | 1098 | WP_001173297.1 | AAA family ATPase | - |
| D6T62_RS06665 | 1249633..1249893 | - | 261 | WP_005135630.1 | host-nuclease inhibitor Gam family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1225149..1283819 | 58670 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T111870 NZ_CP032513:1245358-1245461 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT111870 NZ_CP032513:c1245462-1245228 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
