111834

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 883582..884059 Replicon chromosome
Accession NZ_CP032481
Organism Staphylococcus aureus strain O326

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag SaO326_RS04430 Protein ID WP_000052076.1
Coordinates 883582..883770 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag SaO326_RS04435 Protein ID WP_001059690.1
Coordinates 883799..884059 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO326_RS04400 879626..880096 + 471 WP_000824470.1 hypothetical protein -
SaO326_RS04405 880437..881123 + 687 WP_001804081.1 thermonuclease family protein -
SaO326_RS04410 881475..881675 + 201 WP_001059082.1 cold-shock protein -
SaO326_RS04415 882173..882391 - 219 WP_000005880.1 hypothetical protein -
SaO326_RS04420 882453..882737 - 285 WP_001004401.1 hypothetical protein -
SaO326_RS04425 882825..883394 - 570 WP_001106650.1 hypothetical protein -
SaO326_RS04430 883582..883770 - 189 WP_000052076.1 hypothetical protein Toxin
SaO326_RS04435 883799..884059 - 261 WP_001059690.1 hypothetical protein Antitoxin
SaO326_RS04440 884400..884603 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
SaO326_RS04445 884600..884836 - 237 WP_000368687.1 hypothetical protein -
SaO326_RS04450 885061..885642 + 582 WP_001140691.1 phosphoglycerate mutase family protein -
SaO326_RS04455 885715..886332 - 618 WP_000255563.1 LysE/ArgO family amino acid transporter -
SaO326_RS04460 886488..886982 - 495 WP_000569881.1 GNAT family N-acetyltransferase -
SaO326_RS04465 887381..887803 - 423 WP_000974454.1 organic hydroperoxide resistance protein -
SaO326_RS04470 887951..888667 + 717 WP_000150031.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin VapB-like

(2-69)


Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T111834 WP_000052076.1 NZ_CP032481:c883770-883582 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

>T111834 NZ_CP032481:c883770-883582 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTTTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTCGGATTCGCTATTTTAA
TATACACATTTATATTTGGTGTACTATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT111834 WP_001059690.1 NZ_CP032481:c884059-883799 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp

>AT111834 NZ_CP032481:c884059-883799 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATAAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References