Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 548473..549043 Replicon chromosome
Accession NZ_CP032479
Organism Helicobacter pylori strain 21-F-EK1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D4I21_RS02795 Protein ID WP_139542898.1
Coordinates 548771..549043 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D4I21_RS02790 Protein ID WP_139542897.1
Coordinates 548473..548784 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4I21_RS02760 544458..545105 - 648 Protein_513 hypothetical protein -
D4I21_RS02780 545495..547699 + 2205 WP_139542896.1 outer membrane beta-barrel protein -
D4I21_RS02790 548473..548784 + 312 WP_139542897.1 hypothetical protein Antitoxin
D4I21_RS02795 548771..549043 + 273 WP_139542898.1 type II toxin-antitoxin system mRNA interferase toxin, HP0892 family Toxin
D4I21_RS02800 549152..549676 - 525 WP_033592703.1 acyl-CoA thioesterase -
D4I21_RS02805 549816..550664 + 849 WP_139542899.1 SDR family oxidoreductase -
D4I21_RS02810 550657..551637 + 981 WP_000921449.1 iron ABC transporter permease -
D4I21_RS02815 551637..552404 + 768 WP_139542900.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10511.49 Da        Isoelectric Point: 9.9378

>T111826 WP_139542898.1 NZ_CP032479:548771-549043 [Helicobacter pylori]
MLTIETSKKFDKDLKILVKNGFDLKLLYKVVENLAKEQPLAPKYKDHPLKGGLKDFRECHLKPDLLLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T111826 NZ_CP032479:548771-549043 [Helicobacter pylori]
ATGCTGACGATTGAAACCAGTAAAAAATTTGATAAGGATCTTAAAATTCTTGTTAAAAACGGGTTTGATTTAAAACTTTT
GTATAAAGTGGTTGAAAATTTAGCCAAAGAGCAACCCCTAGCTCCCAAATACAAAGATCACCCACTCAAAGGCGGTTTAA
AAGATTTTAGGGAATGCCACCTAAAACCGGATTTATTGCTTGTCTATCAAATCAAAAAACAAGAAAACACCCTCTTTTTA
GTAAGACTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12305.17 Da        Isoelectric Point: 10.3856

>AT111826 WP_139542897.1 NZ_CP032479:548473-548784 [Helicobacter pylori]
MPNTTAKKDYTKYSQRQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT111826 NZ_CP032479:548473-548784 [Helicobacter pylori]
ATGCCTAACACCACCGCCAAAAAAGACTACACAAAATACAGCCAAAGACAGCTTTTTAACTTTTTAAATTCTATCAAGAC
CAAACAAAAAAGAGCGTTAGAAAAATTGAAGGAAATCCAAGCTCAAAAACAAAGAATCAAAAAAGCGCTCCAATTTAAAG
CACTCCATTTAACCGAAAACGGATACACCATAGAAGAAGAGCGAGAAATCTTAGCAAGGGCTAAAGATACCAAGAACCAC
CTTTGTTTTAAAAGCGTAGAGGATTTTAAGAAGCATTGTGAAAACTTAAGATTTAAAAATGCTGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References