Detailed information of TA system TA111806

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RHH
• Location: 2035125..2035638
• Replicon: chromosome
• Accession: NZ_CP032456
• Organism: Pseudomonas savastanoi strain CAS03

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: D5S10_RS09020
• Protein ID: WP_004658391.1
• Coordinates: 2035125..2035409 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0N8T2X1
• Locus tag: D5S10_RS09025
• Protein ID: WP_029241049.1
• Coordinates: 2035399..2035638 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D5S10_RS09005	2031268..2033196	+	1929	WP_010198401.1	methyl-accepting chemotaxis protein	-
D5S10_RS09010	2033227..2034159	-	933	WP_016982383.1	DMT family transporter	-
D5S10_RS09015	2034234..2035088	+	855	WP_016982382.1	LysR family transcriptional regulator	-
D5S10_RS09020	2035125..2035409	-	285	WP_004658391.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
D5S10_RS09025	2035399..2035638	-	240	WP_029241049.1	CopG family ribbon-helix-helix protein	Antitoxin
D5S10_RS09030	2035798..2036814	-	1017	WP_002552793.1	1-aminocyclopropane-1-carboxylate deaminase	-
D5S10_RS09035	2037001..2037507	+	507	WP_002552794.1	Lrp/AsnC family transcriptional regulator	-
D5S10_RS09040	2037657..2038565	+	909	WP_044294515.1	DUF808 domain-containing protein	-
D5S10_RS09045	2038744..2039529	-	786	WP_002552796.1	membrane protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-41)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10647.31 Da
• Isoelectric Point: 10.4249

>T111806 WP_004658391.1 NZ_CP032456:c2035409-2035125 [Pseudomonas savastanoi]
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Nucleotide

• Length: 285 bp

>T111806 NZ_CP032456:c2035409-2035125 [Pseudomonas savastanoi]
ATGCAGGTTGAGTGGCTTAAAACGGCGCTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACAGGACAATCCAGCTGC
TGCCGCAGCTTTCGTGAAAGCAATTCAATCAAGCGTGACGCAGCTCGCGAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCGCATCCGTAGCGGCCGGCTACAGGTT
CTAAGGATTTTCCACACCAGAAGACAATCGCCCCCCGTGTGGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8715.80 Da
• Isoelectric Point: 4.4354

>AT111806 WP_029241049.1 NZ_CP032456:c2035638-2035399 [Pseudomonas savastanoi]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFANTEDVKAVMDKWSGNAG

Nucleotide

• Length: 240 bp

>AT111806 NZ_CP032456:c2035638-2035399 [Pseudomonas savastanoi]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCGGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACTCGCGAGGCATGGCAGATTGCCGAAATTCAGCGCGCGATTG
AAGAAGCCGACGCTGGCGAGTTCGCCAATACAGAGGACGTAAAAGCTGTCATGGACAAATGGTCTGGCAATGCAGGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A0N8T2X1