Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
Location | 1584645..1586051 | Replicon | chromosome |
Accession | NZ_CP032419 | ||
Organism | Pseudomonas sp. K2W31S-8 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | D3880_RS07365 | Protein ID | WP_119892831.1 |
Coordinates | 1584645..1585214 (+) | Length | 190 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | D3880_RS07370 | Protein ID | WP_119892832.1 |
Coordinates | 1585218..1586051 (+) | Length | 278 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D3880_RS07355 | 1579753..1580574 | + | 822 | WP_119892829.1 | MerR family transcriptional regulator | - |
D3880_RS07360 | 1580796..1584272 | - | 3477 | WP_119892830.1 | hybrid sensor histidine kinase/response regulator | - |
D3880_RS07365 | 1584645..1585214 | + | 570 | WP_119892831.1 | GNAT family N-acetyltransferase | Toxin |
D3880_RS07370 | 1585218..1586051 | + | 834 | WP_119892832.1 | AraC family transcriptional regulator | Antitoxin |
D3880_RS07375 | 1586227..1586940 | + | 714 | WP_119892833.1 | AzlC family ABC transporter permease | - |
D3880_RS07380 | 1586940..1587269 | + | 330 | WP_119892834.1 | AzlD domain-containing protein | - |
D3880_RS07385 | 1587386..1589470 | + | 2085 | WP_119892835.1 | TonB-dependent siderophore receptor | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21415.65 Da Isoelectric Point: 9.7696
>T111766 WP_119892831.1 NZ_CP032419:1584645-1585214 [Pseudomonas sp. K2W31S-8]
MFKPQLIALQRGALRLEPMVDGDIPALVELAEANRDELGYMSGPLRLDWYRSALNDQRNGLALPLCIRLGDRLVGTTRYA
EFLNTLPAAEIGWTWLERGQHGTGLNTTIKYLMLRHAFESWRMVRVQLKTAGSNLRSQRAIEKLGAVREGVLRNHRRLAD
GRLDDTVMYSITDGEWPAVKQQLEARFGA
MFKPQLIALQRGALRLEPMVDGDIPALVELAEANRDELGYMSGPLRLDWYRSALNDQRNGLALPLCIRLGDRLVGTTRYA
EFLNTLPAAEIGWTWLERGQHGTGLNTTIKYLMLRHAFESWRMVRVQLKTAGSNLRSQRAIEKLGAVREGVLRNHRRLAD
GRLDDTVMYSITDGEWPAVKQQLEARFGA
Download Length: 570 bp
>T111766 NZ_CP032419:1584645-1585214 [Pseudomonas sp. K2W31S-8]
ATGTTCAAGCCGCAATTGATCGCACTGCAGCGTGGCGCGCTGCGTCTGGAACCCATGGTCGATGGCGATATCCCGGCGCT
GGTGGAGCTGGCCGAGGCCAATCGCGACGAGTTGGGCTATATGAGCGGGCCGTTGCGCCTGGACTGGTATCGTAGCGCGC
TCAACGATCAGCGCAATGGCCTGGCCCTGCCACTGTGCATCCGCCTCGGTGATCGTCTGGTCGGCACCACGCGCTATGCC
GAGTTTCTCAACACCTTGCCGGCCGCCGAGATCGGTTGGACCTGGTTGGAGCGCGGCCAGCACGGCACCGGCCTGAACAC
CACGATCAAGTACCTGATGCTGCGCCATGCCTTCGAGAGCTGGCGCATGGTCCGTGTGCAGTTGAAAACCGCCGGCAGCA
ACCTGCGCTCGCAGCGCGCCATCGAGAAGCTCGGCGCGGTGCGCGAGGGTGTGCTGCGCAATCACCGGCGCCTGGCCGAC
GGCCGCCTGGACGACACCGTGATGTACAGCATTACCGACGGCGAGTGGCCGGCGGTGAAGCAGCAGCTGGAGGCGCGCTT
CGGCGCCTGA
ATGTTCAAGCCGCAATTGATCGCACTGCAGCGTGGCGCGCTGCGTCTGGAACCCATGGTCGATGGCGATATCCCGGCGCT
GGTGGAGCTGGCCGAGGCCAATCGCGACGAGTTGGGCTATATGAGCGGGCCGTTGCGCCTGGACTGGTATCGTAGCGCGC
TCAACGATCAGCGCAATGGCCTGGCCCTGCCACTGTGCATCCGCCTCGGTGATCGTCTGGTCGGCACCACGCGCTATGCC
GAGTTTCTCAACACCTTGCCGGCCGCCGAGATCGGTTGGACCTGGTTGGAGCGCGGCCAGCACGGCACCGGCCTGAACAC
CACGATCAAGTACCTGATGCTGCGCCATGCCTTCGAGAGCTGGCGCATGGTCCGTGTGCAGTTGAAAACCGCCGGCAGCA
ACCTGCGCTCGCAGCGCGCCATCGAGAAGCTCGGCGCGGTGCGCGAGGGTGTGCTGCGCAATCACCGGCGCCTGGCCGAC
GGCCGCCTGGACGACACCGTGATGTACAGCATTACCGACGGCGAGTGGCCGGCGGTGAAGCAGCAGCTGGAGGCGCGCTT
CGGCGCCTGA
Antitoxin
Download Length: 278 a.a. Molecular weight: 30657.22 Da Isoelectric Point: 9.5211
>AT111766 WP_119892832.1 NZ_CP032419:1585218-1586051 [Pseudomonas sp. K2W31S-8]
MAAVDKERTRFWRAEGLGGVELLHARYIEQRFAPHVHEGFVFTVIEHGAQRFRHRGSEHLAPVGSMVLISPDEVHTGSKA
HEQGWRYRAFYPDIERVSGVLAELELGRNGLPSFAASVLQDPQMALVFIGLHRLLDSGASALQQQTAWREAILLLFQCHA
RIPAAPAPGQEPQAVVRAKELLASRLLAPPSLEELAAAVALSPFHFSRVFRRATGLPPHAWLQQRRLEQARTLLKQGCAP
LAVAMQLGFADQSHLSRQFKQAYGVAPGEYCKACGRS
MAAVDKERTRFWRAEGLGGVELLHARYIEQRFAPHVHEGFVFTVIEHGAQRFRHRGSEHLAPVGSMVLISPDEVHTGSKA
HEQGWRYRAFYPDIERVSGVLAELELGRNGLPSFAASVLQDPQMALVFIGLHRLLDSGASALQQQTAWREAILLLFQCHA
RIPAAPAPGQEPQAVVRAKELLASRLLAPPSLEELAAAVALSPFHFSRVFRRATGLPPHAWLQQRRLEQARTLLKQGCAP
LAVAMQLGFADQSHLSRQFKQAYGVAPGEYCKACGRS
Download Length: 834 bp
>AT111766 NZ_CP032419:1585218-1586051 [Pseudomonas sp. K2W31S-8]
ATGGCGGCGGTCGATAAGGAGCGCACGCGCTTCTGGCGGGCTGAAGGGCTGGGTGGCGTCGAGTTGTTGCATGCGCGTTA
CATCGAGCAGCGTTTCGCCCCGCATGTGCACGAGGGGTTCGTCTTTACCGTGATCGAGCATGGCGCCCAGCGCTTTCGCC
ATCGCGGCAGCGAGCATCTGGCGCCGGTCGGCAGCATGGTGCTGATCAGTCCGGACGAGGTGCATACCGGCTCCAAGGCC
CATGAACAGGGCTGGCGCTACCGGGCCTTCTACCCGGATATCGAGCGGGTCAGCGGGGTGCTGGCGGAGCTCGAGTTGGG
GCGCAATGGCTTGCCGTCGTTCGCCGCCAGCGTGCTGCAGGACCCGCAGATGGCCCTGGTGTTTATCGGCCTGCACCGCC
TGCTGGACAGTGGCGCCAGCGCGTTGCAGCAGCAGACCGCCTGGCGCGAGGCGATTCTCCTGCTGTTCCAGTGCCATGCG
CGGATTCCCGCAGCGCCAGCGCCGGGGCAGGAGCCACAGGCCGTGGTGCGGGCCAAGGAATTGCTCGCCAGCCGCTTGCT
CGCGCCACCGTCGCTGGAGGAGTTGGCCGCCGCGGTGGCCTTGTCGCCGTTCCATTTCTCCCGGGTATTCCGCCGCGCCA
CCGGCCTGCCGCCGCATGCCTGGCTCCAGCAGCGCCGGCTGGAGCAGGCGCGGACGCTGCTCAAGCAGGGCTGCGCGCCA
CTGGCGGTGGCCATGCAGCTGGGCTTCGCCGACCAGAGCCACCTGAGCCGCCAGTTCAAGCAGGCTTACGGCGTGGCACC
CGGCGAATACTGCAAGGCCTGCGGCCGTTCGTAG
ATGGCGGCGGTCGATAAGGAGCGCACGCGCTTCTGGCGGGCTGAAGGGCTGGGTGGCGTCGAGTTGTTGCATGCGCGTTA
CATCGAGCAGCGTTTCGCCCCGCATGTGCACGAGGGGTTCGTCTTTACCGTGATCGAGCATGGCGCCCAGCGCTTTCGCC
ATCGCGGCAGCGAGCATCTGGCGCCGGTCGGCAGCATGGTGCTGATCAGTCCGGACGAGGTGCATACCGGCTCCAAGGCC
CATGAACAGGGCTGGCGCTACCGGGCCTTCTACCCGGATATCGAGCGGGTCAGCGGGGTGCTGGCGGAGCTCGAGTTGGG
GCGCAATGGCTTGCCGTCGTTCGCCGCCAGCGTGCTGCAGGACCCGCAGATGGCCCTGGTGTTTATCGGCCTGCACCGCC
TGCTGGACAGTGGCGCCAGCGCGTTGCAGCAGCAGACCGCCTGGCGCGAGGCGATTCTCCTGCTGTTCCAGTGCCATGCG
CGGATTCCCGCAGCGCCAGCGCCGGGGCAGGAGCCACAGGCCGTGGTGCGGGCCAAGGAATTGCTCGCCAGCCGCTTGCT
CGCGCCACCGTCGCTGGAGGAGTTGGCCGCCGCGGTGGCCTTGTCGCCGTTCCATTTCTCCCGGGTATTCCGCCGCGCCA
CCGGCCTGCCGCCGCATGCCTGGCTCCAGCAGCGCCGGCTGGAGCAGGCGCGGACGCTGCTCAAGCAGGGCTGCGCGCCA
CTGGCGGTGGCCATGCAGCTGGGCTTCGCCGACCAGAGCCACCTGAGCCGCCAGTTCAAGCAGGCTTACGGCGTGGCACC
CGGCGAATACTGCAAGGCCTGCGGCCGTTCGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|