Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1573023..1574180 Replicon chromosome
Accession NZ_CP032419
Organism Pseudomonas sp. K2W31S-8

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag D3880_RS07325 Protein ID WP_177412159.1
Coordinates 1573422..1574180 (+) Length 253 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag D3880_RS07320 Protein ID WP_119892823.1
Coordinates 1573023..1573394 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3880_RS07290 1568435..1568908 - 474 WP_119892818.1 peroxiredoxin -
D3880_RS07295 1568919..1569479 - 561 WP_119892819.1 glycine cleavage system protein R -
D3880_RS07300 1569647..1570525 + 879 WP_119892820.1 4-hydroxy-tetrahydrodipicolinate synthase -
D3880_RS07305 1570544..1571665 + 1122 WP_119892821.1 outer membrane protein assembly factor BamC -
D3880_RS07310 1571777..1572646 + 870 WP_119892822.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
D3880_RS07320 1573023..1573394 + 372 WP_119892823.1 XRE family transcriptional regulator Antitoxin
D3880_RS07325 1573422..1574180 + 759 WP_177412159.1 RES family NAD+ phosphorylase Toxin
D3880_RS07330 1574726..1575127 + 402 WP_119892824.1 sel1 repeat family protein -
D3880_RS07335 1575295..1576653 + 1359 WP_162935044.1 DNA recombination protein RmuC -
D3880_RS07340 1576755..1577648 - 894 WP_119892826.1 metal-dependent hydrolase -
D3880_RS07345 1577703..1578623 - 921 WP_119892827.1 alpha/beta fold hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(65-208)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-47)


Sequences

Toxin        


Download         Length: 253 a.a.        Molecular weight: 28378.37 Da        Isoelectric Point: 6.6372

>T111765 WP_177412159.1 NZ_CP032419:1573422-1574180 [Pseudomonas sp. K2W31S-8]
MTVDIWQLCHGPEQVAPLRGQLVRLVESQEQVATLRLVDSLAEQALLEDLIEGSKPPLPTGTEALHYLLKTPFRYPPLRW
GSRFGSVYEPSLFYAGARLETAMAETAYYRCVLWDGMLSPPPSGRILSEHASFEVRYRVERGVRLQVPPFAEFQAELSDP
RRYAATQALGQAMRTAGVEAFEYRSARCPQGGTNVALYTPRAFSEKQPRNLTPWLCETTADYVAFKHAQAPDAPRLFHWQ
QFLVDGQLPLPA

Download         Length: 759 bp

>T111765 NZ_CP032419:1573422-1574180 [Pseudomonas sp. K2W31S-8]
ATGACCGTGGATATCTGGCAGCTTTGCCATGGGCCTGAGCAGGTCGCCCCGTTACGCGGCCAATTGGTGCGGCTGGTGGA
AAGCCAGGAGCAGGTTGCTACCTTGCGTCTGGTCGACAGCCTGGCCGAGCAGGCGCTGCTGGAAGACTTGATCGAAGGCA
GCAAGCCGCCGCTGCCGACGGGCACGGAAGCGCTTCATTACCTGCTGAAGACGCCGTTCCGCTACCCGCCGCTGCGCTGG
GGCTCGCGTTTCGGCAGTGTCTACGAACCCAGCCTGTTCTATGCCGGCGCGCGTCTGGAAACCGCCATGGCCGAGACCGC
CTATTACCGCTGCGTGCTGTGGGATGGCATGCTCAGTCCGCCGCCGAGTGGGCGCATCCTATCCGAGCATGCCTCGTTCG
AGGTGCGTTATCGGGTCGAGCGGGGCGTGCGCCTGCAGGTGCCGCCCTTTGCCGAATTTCAGGCCGAGCTGAGCGATCCC
AGGCGTTATGCCGCCACCCAGGCGTTGGGCCAAGCGATGCGCACCGCCGGGGTCGAGGCGTTCGAGTACCGTTCGGCGCG
CTGCCCGCAAGGGGGCACCAATGTCGCGTTGTATACCCCGCGGGCGTTCAGTGAAAAGCAGCCGCGTAACCTGACGCCTT
GGCTGTGCGAAACCACGGCCGACTATGTCGCCTTCAAACATGCCCAGGCGCCCGACGCGCCGCGGCTGTTCCACTGGCAG
CAGTTTCTCGTCGACGGGCAATTGCCGCTGCCGGCATAG

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13654.86 Da        Isoelectric Point: 10.3988

>AT111765 WP_119892823.1 NZ_CP032419:1573023-1573394 [Pseudomonas sp. K2W31S-8]
MSALTRPQLDAEAVLARALLNAREQLGLTQQELAEIVGVHRTAVTRWADSGGLRPQSKTGELALLLIRVYRALFALFGGN
LDDMRHFLRTENRHLAGVPLQQMAQVQGLVRLVEYLDAIRGKV

Download         Length: 372 bp

>AT111765 NZ_CP032419:1573023-1573394 [Pseudomonas sp. K2W31S-8]
ATGAGTGCGCTCACCCGTCCGCAGTTGGATGCCGAAGCAGTACTGGCCAGGGCCCTGCTCAATGCTCGCGAGCAATTGGG
GCTGACCCAGCAGGAGCTGGCGGAGATCGTCGGCGTACACCGCACGGCTGTCACCCGCTGGGCGGACAGCGGTGGTTTGC
GTCCGCAGAGCAAGACCGGTGAATTGGCGCTGTTGCTGATCCGGGTCTACCGCGCGCTGTTCGCCTTGTTCGGTGGCAAT
CTCGATGACATGCGTCACTTTCTGCGCACCGAGAACCGTCATCTGGCCGGCGTGCCTTTGCAGCAGATGGCTCAGGTGCA
AGGGCTGGTGCGGCTAGTGGAGTACCTGGATGCCATTCGCGGCAAGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References