Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2029043..2030592 Replicon chromosome
Accession NZ_CP032415
Organism Shewanella algae strain VGH117

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag D3X10_RS09895 Protein ID WP_117200307.1
Coordinates 2029291..2030592 (+) Length 434 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag D3X10_RS09890 Protein ID WP_025011264.1
Coordinates 2029043..2029291 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3X10_RS09875 (D3X10_09920) 2024494..2026419 + 1926 WP_117200309.1 U32 family peptidase -
D3X10_RS09880 (D3X10_09925) 2026430..2026804 + 375 WP_014386412.1 PH domain-containing protein -
D3X10_RS09885 (D3X10_09930) 2026816..2028531 - 1716 WP_117200308.1 ATP-binding cassette domain-containing protein -
D3X10_RS09890 (D3X10_09935) 2029043..2029291 + 249 WP_025011264.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
D3X10_RS09895 (D3X10_09940) 2029291..2030592 + 1302 WP_117200307.1 type II toxin-antitoxin system HipA family toxin Toxin
D3X10_RS09900 (D3X10_09945) 2030733..2032100 - 1368 WP_028781110.1 L-cystine transporter -
D3X10_RS09905 (D3X10_09950) 2032404..2034431 + 2028 WP_117200306.1 S9 family peptidase -
D3X10_RS09910 (D3X10_09955) 2034508..2035092 - 585 WP_117200305.1 LysE family translocator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(15-64)


Sequences

Toxin        


Download         Length: 434 a.a.        Molecular weight: 48587.38 Da        Isoelectric Point: 9.5377

>T111761 WP_117200307.1 NZ_CP032415:2029291-2030592 [Shewanella algae]
MQKLIAYMNGELVGTLAKHKNGAHTFQYDKDWITNAMARPLSLSLRLQLPPITSDAVINYFDNLLPDSPQVRDRIVARYK
ASSKQPFDLLKEIGKDSVGAIALFPPEHPYKKEPLSYEILDNKKLEAVLSAYKSDIPLGMLKEEEDFRISVAGAQEKTAL
LFIDGQWCIPKGNTPTTHIIKLPIGEIPQASATLDLKDSVENEYLCIELAKALGFAVPSVNIIKTDNLKALAVERFDRRW
TKDRAGLLRLPQEDICQVFGMPSSIKYESQGGPGIAQIMKLLMGSSNALEDRYNFMRFQVFQWIIGATDGHAKNFSIYID
RGGSYRLTPFYDILSAYPLLGGKGLNIRQLKLAMGLKATKGKKYEINKILPRHFLDTAKAVNFSQDKMQRIMDEMKGALP
EAISHVRANLPEGFPEHISNSIFENAKKTIKKI

Download         Length: 1302 bp

>T111761 NZ_CP032415:2029291-2030592 [Shewanella algae]
ATGCAAAAGCTAATAGCATACATGAATGGTGAACTTGTTGGCACCTTGGCGAAGCATAAAAACGGCGCTCACACTTTTCA
ATATGATAAGGACTGGATAACCAATGCAATGGCTCGCCCACTGTCATTGTCTTTGAGGCTTCAATTACCACCTATTACTT
CCGATGCCGTTATCAACTATTTTGACAACCTCTTACCAGACAGCCCACAAGTCAGAGACAGAATCGTTGCAAGGTACAAA
GCCTCATCCAAACAACCATTTGATCTTTTGAAAGAAATTGGAAAGGATAGTGTTGGTGCTATTGCACTATTTCCTCCCGA
ACACCCCTATAAAAAAGAGCCACTCAGCTACGAAATATTGGATAACAAGAAACTAGAAGCCGTTCTTTCTGCATACAAGT
CTGATATTCCCCTCGGAATGCTCAAAGAGGAAGAAGACTTTAGGATCTCAGTGGCAGGTGCTCAAGAAAAAACCGCACTC
TTATTCATTGATGGACAATGGTGTATACCGAAAGGAAACACGCCAACCACTCACATTATCAAGCTGCCAATAGGCGAAAT
ACCACAAGCTAGCGCGACACTGGATCTCAAAGATAGCGTAGAAAATGAATATCTTTGCATTGAGCTAGCTAAAGCGCTGG
GATTCGCAGTTCCCAGCGTCAATATAATCAAAACAGACAACCTTAAAGCTTTAGCTGTAGAACGATTTGATCGACGCTGG
ACAAAAGACAGAGCAGGCTTGCTACGCTTACCTCAAGAAGATATTTGCCAAGTGTTTGGTATGCCATCATCCATCAAATA
TGAATCTCAAGGTGGTCCAGGCATAGCACAGATCATGAAGTTATTAATGGGCTCAAGTAATGCACTTGAAGATCGATATA
ACTTCATGAGATTCCAGGTATTTCAATGGATCATTGGGGCTACGGATGGACATGCTAAAAACTTTTCTATCTATATTGAT
AGAGGAGGTAGCTATCGACTCACTCCATTCTACGACATTCTTTCAGCCTACCCATTACTGGGAGGAAAAGGACTCAATAT
TCGACAACTTAAGCTCGCAATGGGGTTAAAAGCCACAAAAGGCAAGAAGTATGAAATCAATAAAATCCTGCCTCGTCACT
TTTTAGATACTGCTAAAGCTGTGAATTTTAGTCAGGATAAGATGCAAAGAATAATGGATGAAATGAAAGGTGCGTTACCT
GAGGCAATCTCGCATGTAAGGGCGAATCTACCGGAGGGCTTTCCAGAGCATATCTCCAACTCAATTTTTGAGAATGCCAA
GAAAACAATTAAAAAAATCTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9366.70 Da        Isoelectric Point: 6.2564

>AT111761 WP_025011264.1 NZ_CP032415:2029043-2029291 [Shewanella algae]
MIYSPKQLADMMLLIRQKNGWTQSELAKKVGIKQATISNFENNPNKTTLSTFFKLVQAMDLTLSIQEKTQLTSPSENDDE
SW

Download         Length: 249 bp

>AT111761 NZ_CP032415:2029043-2029291 [Shewanella algae]
ATGATATATAGTCCAAAGCAACTCGCAGACATGATGCTACTGATACGCCAAAAGAATGGCTGGACTCAATCAGAGTTGGC
GAAAAAAGTCGGTATAAAGCAAGCGACAATCTCGAACTTCGAGAACAACCCCAACAAAACAACGCTTTCTACCTTCTTTA
AGCTTGTACAAGCTATGGATCTAACACTGAGTATCCAAGAAAAAACACAGCTGACTTCGCCAAGTGAAAATGATGATGAG
AGTTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References