111753

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2869625..2870202 Replicon chromosome
Accession NZ_CP032405
Organism Rhizobium rosettiformans strain MAE2-X

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D4A92_RS13985 Protein ID WP_203014220.1
Coordinates 2869837..2870202 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D4A92_RS13980 Protein ID WP_185810907.1
Coordinates 2869625..2869843 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4A92_RS13965 2864782..2866380 - 1599 WP_203014212.1 peptide ABC transporter substrate-binding protein -
D4A92_RS13970 2866630..2867988 - 1359 WP_203014214.1 glutamine synthetase family protein -
D4A92_RS13975 2868181..2869554 + 1374 WP_203014217.1 aspartate aminotransferase family protein -
D4A92_RS13980 2869625..2869843 + 219 WP_185810907.1 ribbon-helix-helix domain-containing protein Antitoxin
D4A92_RS13985 2869837..2870202 + 366 WP_203014220.1 type II toxin-antitoxin system VapC family toxin Toxin
D4A92_RS13990 2870221..2870994 - 774 WP_203014223.1 SDR family oxidoreductase -
D4A92_RS13995 2871077..2871370 - 294 WP_203014226.1 DUF2218 domain-containing protein -
D4A92_RS14000 2871373..2871963 - 591 WP_203014229.1 PadR family transcriptional regulator -
D4A92_RS14005 2872114..2872587 + 474 WP_203014231.1 OsmC family protein -
D4A92_RS14010 2872614..2873498 - 885 WP_203014234.1 LysR family transcriptional regulator -
D4A92_RS14015 2873605..2874705 + 1101 WP_203014237.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-109)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13415.85 Da        Isoelectric Point: 8.5948

>T111753 WP_203014220.1 NZ_CP032405:2869837-2870202 [Rhizobium rosettiformans]
MVKVLFDTNIVIDVLRGVPPAQDVMISYPERAVSIISWMEVMVGAPATLSDATRAFLRGFELIGLTESIANQAVVVRQVH
KLKLPDAVIWATAKVHGLKLLTRDTKGFPRQHPDIIVPYEL

Download         Length: 366 bp

>T111753 NZ_CP032405:2869837-2870202 [Rhizobium rosettiformans]
ATGGTGAAGGTCCTCTTCGACACCAACATCGTGATCGATGTGCTTAGGGGAGTTCCTCCTGCTCAGGACGTGATGATCAG
TTATCCGGAGCGCGCAGTCAGTATCATCAGCTGGATGGAGGTCATGGTTGGCGCGCCCGCGACGCTCAGTGATGCAACAC
GAGCATTTTTGCGAGGGTTCGAACTGATTGGCCTTACGGAAAGCATCGCCAATCAGGCCGTTGTCGTAAGGCAGGTTCAC
AAACTCAAATTGCCGGACGCAGTCATCTGGGCGACAGCAAAGGTGCATGGTCTGAAATTGCTGACGCGCGACACCAAAGG
TTTTCCGCGTCAGCACCCCGATATCATCGTACCTTACGAACTCTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8177.24 Da        Isoelectric Point: 4.2463

>AT111753 WP_185810907.1 NZ_CP032405:2869625-2869843 [Rhizobium rosettiformans]
MRTLVDIPEEDIEALDRLAAQRNVSRASLIREAVGELLDRQKDDIVLDGFGLWAGSETEDGLIIQRKLRAEW

Download         Length: 219 bp

>AT111753 NZ_CP032405:2869625-2869843 [Rhizobium rosettiformans]
ATGCGTACGCTGGTCGACATTCCGGAAGAGGATATTGAGGCGCTGGACAGGCTCGCGGCTCAACGGAATGTGTCGCGTGC
ATCTCTGATCAGAGAAGCGGTCGGTGAACTTCTGGATCGACAGAAGGACGATATTGTTCTGGACGGTTTCGGGCTATGGG
CTGGTTCGGAGACTGAAGATGGCCTGATCATTCAGCGGAAACTTCGCGCCGAATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References