111751

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 2668921..2669520 Replicon chromosome
Accession NZ_CP032405
Organism Rhizobium rosettiformans strain MAE2-X

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D4A92_RS12875 Protein ID WP_203013730.1
Coordinates 2668921..2669166 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D4A92_RS12880 Protein ID WP_203013732.1
Coordinates 2669170..2669520 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4A92_RS12850 2665150..2666292 + 1143 WP_203013715.1 alpha/beta fold hydrolase -
D4A92_RS12855 2666486..2666569 + 84 WP_203019950.1 hypothetical protein -
D4A92_RS12860 2666634..2666912 + 279 WP_203013717.1 prevent-host-death protein -
D4A92_RS12865 2666909..2667214 + 306 WP_203013718.1 type II toxin-antitoxin system RelE/ParE family toxin -
D4A92_RS12870 2667218..2668870 - 1653 WP_203013728.1 choline dehydrogenase -
D4A92_RS12875 2668921..2669166 + 246 WP_203013730.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
D4A92_RS12880 2669170..2669520 + 351 WP_203013732.1 helix-turn-helix transcriptional regulator Antitoxin
D4A92_RS12885 2669747..2671210 - 1464 WP_203013734.1 betaine-aldehyde dehydrogenase -
D4A92_RS12890 2671322..2671954 - 633 WP_203013736.1 transcriptional regulator BetI -
D4A92_RS12895 2672278..2674101 + 1824 WP_203013738.1 GGDEF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(60-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9390.10 Da        Isoelectric Point: 11.1642

>T111751 WP_203013730.1 NZ_CP032405:2668921-2669166 [Rhizobium rosettiformans]
MKKVEYSRAASKVLDRMQPRRREAIRQKVDAFARGERVDLKKLKGSPLLRIRVGDDRVIIDEQRMLVLVVEVGPRGGIYK
E

Download         Length: 246 bp

>T111751 NZ_CP032405:2668921-2669166 [Rhizobium rosettiformans]
ATGAAGAAGGTGGAGTATTCTAGGGCCGCCAGCAAAGTGTTGGACCGGATGCAGCCCAGGCGACGGGAGGCGATCCGCCA
GAAAGTCGATGCGTTCGCACGAGGCGAGCGGGTCGATTTGAAGAAGCTGAAGGGCAGCCCGCTTCTCAGAATTCGCGTCG
GAGACGACCGGGTCATCATCGATGAGCAGAGGATGCTGGTCCTTGTCGTCGAAGTCGGGCCGCGCGGCGGCATCTACAAG
GAGTGA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 13017.74 Da        Isoelectric Point: 4.2556

>AT111751 WP_203013732.1 NZ_CP032405:2669170-2669520 [Rhizobium rosettiformans]
MGELRKTVIDGETYVLIPEDEYEDLIDGIEAEKILARVRAGEETWPAELVYELWETDSRIRTYRNYRKLSVSDLAAAAGI
SQPYLSEIESGKKTGSVDVLKRIAAALKVDLDDIVV

Download         Length: 351 bp

>AT111751 NZ_CP032405:2669170-2669520 [Rhizobium rosettiformans]
ATGGGCGAACTGCGCAAGACCGTCATCGACGGCGAGACCTATGTTCTCATCCCCGAGGACGAGTACGAAGACCTGATCGA
TGGCATTGAGGCCGAGAAGATTCTGGCTCGTGTCCGGGCCGGCGAGGAGACCTGGCCGGCGGAACTCGTTTACGAACTCT
GGGAAACCGACAGCCGCATCCGCACCTACCGCAATTACCGCAAGCTGTCCGTCTCCGACCTCGCCGCCGCTGCCGGCATC
TCGCAGCCCTATCTCTCCGAGATCGAGAGCGGCAAGAAGACCGGCTCGGTTGATGTGCTGAAGCGTATTGCCGCGGCGCT
CAAGGTCGATCTCGACGATATCGTGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References