111747

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 472286..472920 Replicon chromosome
Accession NZ_CP032405
Organism Rhizobium rosettiformans strain MAE2-X

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D4A92_RS02365 Protein ID WP_203017849.1
Coordinates 472531..472920 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D4A92_RS02360 Protein ID WP_203017848.1
Coordinates 472286..472534 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4A92_RS02335 467637..468503 - 867 WP_203017840.1 MurR/RpiR family transcriptional regulator -
D4A92_RS02340 468520..468906 - 387 WP_203017842.1 RidA family protein -
D4A92_RS02345 469019..469510 + 492 WP_203017844.1 hypothetical protein -
D4A92_RS02350 469549..471030 + 1482 WP_203017846.1 M81 family metallopeptidase -
D4A92_RS02355 471027..472118 + 1092 WP_203017847.1 D-TA family PLP-dependent enzyme -
D4A92_RS02360 472286..472534 + 249 WP_203017848.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
D4A92_RS02365 472531..472920 + 390 WP_203017849.1 type II toxin-antitoxin system VapC family toxin Toxin
D4A92_RS02370 472965..473399 + 435 Protein_470 GFA family protein -
D4A92_RS02375 473491..473628 - 138 WP_203017850.1 hypothetical protein -
D4A92_RS02380 473862..474992 - 1131 WP_203017851.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
D4A92_RS02385 475093..476313 - 1221 WP_040299437.1 extracellular solute-binding protein -
D4A92_RS02390 476377..477237 - 861 WP_203017852.1 carbohydrate ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-81)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14154.23 Da        Isoelectric Point: 4.9208

>T111747 WP_203017849.1 NZ_CP032405:472531-472920 [Rhizobium rosettiformans]
MIVDTSAMVAIFYGEPEAAGFTRLIHDAAVTRISVANLVELSMVIEKQLGPEGMRQVEAFFRRAAISVEPVTVEQGNLAR
QAFLDFGKGRHRAALNFGDCFAYALAKDLDEPLLFKGKDFTETDIRSAA

Download         Length: 390 bp

>T111747 NZ_CP032405:472531-472920 [Rhizobium rosettiformans]
ATGATTGTCGACACATCAGCCATGGTTGCAATCTTCTACGGCGAACCGGAAGCTGCCGGCTTCACGCGACTGATCCACGA
CGCTGCAGTCACGCGGATCAGCGTCGCTAACCTTGTCGAGCTCTCCATGGTAATCGAAAAGCAGCTCGGCCCGGAGGGAA
TGAGGCAGGTCGAGGCTTTCTTCCGCCGCGCGGCAATCAGCGTTGAGCCAGTGACGGTCGAGCAAGGCAATCTGGCGCGG
CAGGCCTTTCTCGATTTCGGCAAGGGCAGGCATAGAGCTGCACTGAACTTTGGCGACTGCTTTGCCTACGCCCTCGCCAA
AGATCTCGATGAACCGCTGCTATTCAAGGGCAAAGACTTCACGGAGACGGACATTCGCTCGGCAGCGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9047.34 Da        Isoelectric Point: 6.4608

>AT111747 WP_203017848.1 NZ_CP032405:472286-472534 [Rhizobium rosettiformans]
MSLNIKDPEAHRLAQAIALATGQSMSRVVTDALRERYAQLEKQNGKASVDELLMIANRAAALLKQPYADHAELLYDQDGL
PK

Download         Length: 249 bp

>AT111747 NZ_CP032405:472286-472534 [Rhizobium rosettiformans]
ATGAGTCTCAACATAAAAGATCCCGAAGCACATCGCCTTGCTCAGGCGATCGCCCTTGCCACCGGGCAGAGTATGAGCCG
TGTTGTGACCGATGCTCTGCGCGAGCGGTACGCGCAGCTTGAAAAGCAGAATGGCAAGGCTTCCGTCGACGAGCTTTTGA
TGATCGCAAACCGGGCCGCAGCGCTTCTGAAGCAGCCTTACGCCGATCACGCCGAGCTTCTCTATGACCAAGACGGCCTG
CCGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References