Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 359848..360401 Replicon chromosome
Accession NZ_CP032405
Organism Rhizobium rosettiformans strain MAE2-X

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D4A92_RS01800 Protein ID WP_203017706.1
Coordinates 360108..360401 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D4A92_RS01795 Protein ID WP_203017704.1
Coordinates 359848..360120 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4A92_RS01770 355609..356289 + 681 WP_203017695.1 TetR/AcrR family transcriptional regulator -
D4A92_RS01775 356286..357125 - 840 WP_203017697.1 amidohydrolase -
D4A92_RS01780 357146..357952 - 807 WP_203017698.1 IclR family transcriptional regulator -
D4A92_RS01785 358088..358822 + 735 WP_203017700.1 SDR family oxidoreductase -
D4A92_RS01790 358844..359686 + 843 WP_203017702.1 fumarylacetoacetate hydrolase family protein -
D4A92_RS01795 359848..360120 + 273 WP_203017704.1 CopG family ribbon-helix-helix protein Antitoxin
D4A92_RS01800 360108..360401 + 294 WP_203017706.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D4A92_RS01805 360490..361086 - 597 WP_203017708.1 outer membrane beta-barrel protein -
D4A92_RS01810 361332..362834 - 1503 WP_203017709.1 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta -
D4A92_RS01815 362856..364427 - 1572 WP_203017710.1 Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha -
D4A92_RS01820 364689..364853 + 165 WP_006724646.1 DUF1328 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10886.60 Da        Isoelectric Point: 10.3370

>T111746 WP_203017706.1 NZ_CP032405:360108-360401 [Rhizobium rosettiformans]
VPRVIVTEGAAIGLERCRRFLQAGSAEAAQKAAREIKRQFKLLASQPHIGRPMQRAPAIRELSIPFGTSGYVALYRYEAL
EEAVYILAFRHQREAGY

Download         Length: 294 bp

>T111746 NZ_CP032405:360108-360401 [Rhizobium rosettiformans]
GTGCCACGAGTAATCGTGACAGAGGGAGCAGCTATTGGCTTGGAGCGATGCCGTCGCTTCCTTCAGGCAGGGTCGGCGGA
GGCAGCTCAGAAAGCAGCCAGGGAAATCAAACGACAATTCAAGCTGCTGGCGAGCCAACCGCACATCGGAAGACCAATGC
AACGCGCGCCCGCGATTAGGGAATTGAGCATTCCTTTTGGCACCTCGGGCTATGTGGCCCTTTATCGTTATGAAGCGCTG
GAGGAGGCAGTCTACATCCTGGCATTCAGGCATCAGCGCGAAGCGGGATATTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10400.57 Da        Isoelectric Point: 4.5396

>AT111746 WP_203017704.1 NZ_CP032405:359848-360120 [Rhizobium rosettiformans]
MATSLKIDDALKERVQQLANDRKRSAHGLMLEAIEQYVEREEARETFTREALASWTAFKETGRHLTLEEVGDWLETWGTA
DEKPVPECHE

Download         Length: 273 bp

>AT111746 NZ_CP032405:359848-360120 [Rhizobium rosettiformans]
ATGGCGACCTCGCTGAAGATCGATGACGCATTAAAAGAGCGGGTGCAGCAACTGGCCAACGACCGCAAACGCTCGGCGCA
TGGACTGATGCTGGAAGCGATTGAGCAGTATGTGGAGCGTGAGGAGGCCCGTGAGACCTTCACGCGAGAGGCACTGGCAT
CCTGGACGGCTTTCAAGGAAACGGGCCGCCACCTGACACTGGAGGAAGTTGGCGACTGGCTCGAAACCTGGGGCACAGCC
GACGAAAAACCGGTGCCCGAGTGCCACGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References