Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 20778..21421 Replicon plasmid p22429
Accession NZ_CP032397
Organism Salmonella enterica subsp. enterica serovar Dublin strain CVM 22429

Toxin (Protein)


Gene name vagD Uniprot ID V0UN72
Locus tag D5G01_RS25020 Protein ID WP_001034044.1
Coordinates 21005..21421 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID B1P7N7
Locus tag D5G01_RS25015 Protein ID WP_001261286.1
Coordinates 20778..21008 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5G01_RS25005 16604..16792 - 189 WP_000957857.1 hypothetical protein -
D5G01_RS25010 16909..20397 - 3489 Protein_24 pcar -
D5G01_RS25015 20778..21008 + 231 WP_001261286.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
D5G01_RS25020 21005..21421 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin
D5G01_RS25025 21496..23061 + 1566 WP_001128474.1 AAA family ATPase -
D5G01_RS25030 23046..24068 + 1023 WP_000361402.1 helicase UvrD -
D5G01_RS25035 24322..25019 - 698 Protein_29 IS1 family transposase -
D5G01_RS25045 25399..25773 - 375 Protein_30 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..329264 329264


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 17834.22 Da        Isoelectric Point: 12.9398

>T111737 WP_001034044.1 NZ_CP032397:21005-21421 [Salmonella enterica subsp. enterica serovar Dublin]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 417 bp

>T111737 NZ_CP032397:21005-21421 [Salmonella enterica subsp. enterica serovar Dublin]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9887.42 Da        Isoelectric Point: 12.6808

>AT111737 WP_001261286.1 NZ_CP032397:20778-21008 [Salmonella enterica subsp. enterica serovar Dublin]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 231 bp

>AT111737 NZ_CP032397:20778-21008 [Salmonella enterica subsp. enterica serovar Dublin]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829CHW1

Antitoxin

Source ID Structure
AlphaFold DB A0A829CKZ6

References