Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2394146..2394290 Replicon chromosome
Accession NZ_CP032354
Organism Klebsiella variicola strain 15WZ-82

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2394182..2394284 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2394146..2394290 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4N21_RS11890 2389276..2391336 + 2061 WP_012541258.1 oligopeptidase B -
D4N21_RS11895 2391340..2391999 - 660 WP_012541259.1 exodeoxyribonuclease X -
D4N21_RS11900 2392078..2392308 - 231 WP_012541260.1 DNA polymerase III subunit theta -
D4N21_RS11905 2392422..2392796 + 375 WP_012541261.1 CopC domain-containing protein YobA -
D4N21_RS11910 2392800..2393669 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
D4N21_RS11915 2393686..2394024 + 339 WP_008804271.1 YebY family protein -
- 2394146..2394290 - 145 - - Antitoxin
- 2394182..2394284 + 103 - - Toxin
D4N21_RS30700 2394669..2394812 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
D4N21_RS11925 2394916..2395905 - 990 WP_032691211.1 VirK/YbjX family protein -
D4N21_RS11930 2396041..2396694 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
D4N21_RS11935 2396691..2396882 - 192 WP_002911395.1 YebW family protein -
D4N21_RS11940 2396980..2397219 - 240 WP_002911393.1 YebV family protein -
D4N21_RS11945 2397335..2398768 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T111684 NZ_CP032354:2394182-2394284 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT111684 NZ_CP032354:c2394290-2394146 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References