Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 243840..245116 | Replicon | chromosome |
| Accession | NZ_CP032352 | ||
| Organism | Pseudomonas protegens strain pf5-k3 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | Q4KD87 |
| Locus tag | D4N38_RS01005 | Protein ID | WP_011060985.1 |
| Coordinates | 243840..244439 (-) | Length | 200 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | D4N38_RS01010 | Protein ID | WP_011060984.1 |
| Coordinates | 244559..245116 (-) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D4N38_RS00985 | 239642..240070 | + | 429 | WP_011060989.1 | hypothetical protein | - |
| D4N38_RS00990 | 240118..240738 | + | 621 | WP_011060988.1 | hypothetical protein | - |
| D4N38_RS00995 | 240698..241384 | + | 687 | WP_011060987.1 | hypothetical protein | - |
| D4N38_RS01000 | 241446..243626 | - | 2181 | WP_011060986.1 | catalase/peroxidase HPI | - |
| D4N38_RS01005 | 243840..244439 | - | 600 | WP_011060985.1 | HD domain-containing protein | Toxin |
| D4N38_RS01010 | 244559..245116 | - | 558 | WP_011060984.1 | helix-turn-helix domain-containing protein | Antitoxin |
| D4N38_RS01015 | 245306..245647 | + | 342 | WP_011060983.1 | low molecular weight protein tyrosine phosphatase family protein | - |
| D4N38_RS01020 | 245685..246095 | + | 411 | WP_041774583.1 | hypothetical protein | - |
| D4N38_RS01025 | 246274..247460 | - | 1187 | Protein_196 | PrpF protein | - |
| D4N38_RS01030 | 247920..248507 | + | 588 | WP_011060980.1 | inclusion body family protein | - |
| D4N38_RS01035 | 248553..249173 | - | 621 | WP_011060979.1 | LysE family translocator | - |
| D4N38_RS01040 | 249261..249911 | - | 651 | WP_011060978.1 | DUF2239 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 200 a.a. Molecular weight: 22413.22 Da Isoelectric Point: 5.8382
>T111670 WP_011060985.1 NZ_CP032352:c244439-243840 [Pseudomonas protegens]
MNSELLSGRLEFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSPQERADLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDADTQRRLDAQAQAAVQHRLR
MNSELLSGRLEFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSPQERADLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDADTQRRLDAQAQAAVQHRLR
Download Length: 600 bp
>T111670 NZ_CP032352:c244439-243840 [Pseudomonas protegens]
ATGAACAGTGAACTTCTCAGTGGCCGCCTTGAATTCCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGTGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGATCTGGACCTACTGCGGGTGCTGAAGCTGTGCATCGTTCACGACCTGGGGGAGGCCATTCACGGCGATATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCCGCAGGAGCGCGCGGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCAACGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGATGCCAGCCCGCTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCAGCATCGGCTGCGCTAA
ATGAACAGTGAACTTCTCAGTGGCCGCCTTGAATTCCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGTGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGATCTGGACCTACTGCGGGTGCTGAAGCTGTGCATCGTTCACGACCTGGGGGAGGCCATTCACGGCGATATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCCGCAGGAGCGCGCGGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCAACGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGATGCCAGCCCGCTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCAGCATCGGCTGCGCTAA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20446.44 Da Isoelectric Point: 7.4189
>AT111670 WP_011060984.1 NZ_CP032352:c245116-244559 [Pseudomonas protegens]
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEQLLAANLSAAADQALARLVHD
SPRAVHLVCDLTHRLLACSVTRAGQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEQLLAANLSAAADQALARLVHD
SPRAVHLVCDLTHRLLACSVTRAGQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL
Download Length: 558 bp
>AT111670 NZ_CP032352:c245116-244559 [Pseudomonas protegens]
ATGTCCGTAGCTCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAGTTGTTCGGTGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAAGCCATGGAACCGGCGG
AACGCGCGCGCTTGGAGCAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCGCGGCTGGTGCATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCCGTGACCCGCGCCGGGCAGTTCGG
CGTGCCCCTGAGCGAGCTGCTGGGGCAATCCCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTACTGGCCCCGCCGTCCCTGGAATTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTCTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA
ATGTCCGTAGCTCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAGTTGTTCGGTGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAAGCCATGGAACCGGCGG
AACGCGCGCGCTTGGAGCAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCGCGGCTGGTGCATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCCGTGACCCGCGCCGGGCAGTTCGG
CGTGCCCCTGAGCGAGCTGCTGGGGCAATCCCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTACTGGCCCCGCCGTCCCTGGAATTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTCTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|